Interactions for 8U4O (chain J)
Structure details
- PDB ID: 8U4O open_in_new
- Protein: CXCL12_HUMAN
- Organism: Homo sapiens
- UniProt ID: P48061 open_in_new
- Method: Cryo-em
- Resolution: 3.29 Å
- Date: March 13, 2024
- Reference: 10.1101/2024.02.09.579708 open_in_new
- State: monomer
Chemokine diagram
Pick color:
, 'snake_.png', {scale: 3});){kind=link}
, 'snake_.jpg', {scale: 3});){kind=link}
Interactions found in structure
Download list in excel
| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Lys 1 | 55 | N-term | ASP 187 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Lys 1 | 55 | N-term | ASP 187 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Lys 1 | 55 | N-term | TRP 94 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Lys 1 | 55 | N-term | CYS 186 | C-X-C chemokine receptor type 4 (R) | HBDonor |
| Lys 1 | 55 | N-term | CYS 186 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Lys 1 | 55 | N-term | HIS 113 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Lys 1 | 55 | N-term | HIS 113 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Lys 1 | 55 | N-term | ASP 97 | C-X-C chemokine receptor type 4 (R) | Cationic |
| Pro 2 | 56 | N-term | TRP 94 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Pro 2 | 56 | N-term | PHE 292 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Val 3 | 57 | N-term | ILE 284 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Ser 4 | 58 | N-term | HIS 281 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Ser 4 | 58 | N-term | GLU 288 | C-X-C chemokine receptor type 4 (R) | HBDonor |
| Ser 4 | 58 | N-term | GLU 288 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Ser 4 | 58 | N-term | SER 285 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Leu 5 | 59 | N-term | ALA 98 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Leu 5 | 59 | N-term | LEU 41 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Leu 5 | 59 | N-term | TRP 94 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Ser 6 | 60 | N-term | ASP 187 | C-X-C chemokine receptor type 4 (R) | HBDonor |
| Ser 6 | 60 | N-term | ASP 187 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Tyr 7 | 61 | N-term | ASP 187 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Tyr 7 | 61 | N-term | ASP 187 | C-X-C chemokine receptor type 4 (R) | HBDonor |
| Tyr 7 | 61 | N-term | ASP 187 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Arg 8 | 62 | N-term | LEU 266 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Arg 8 | 62 | N-term | ASP 262 | C-X-C chemokine receptor type 4 (R) | Cationic |
| Pro 10 | 66 | CX | PHE 29 | C-X-C chemokine receptor type 4 (R) | Hydrophobic |
| Cys 11 | 67 | CX | PRO 27 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Arg 12 | 68 | N-loop | ASP 193 | C-X-C chemokine receptor type 4 (R) | Cationic |
| Arg 12 | 68 | N-loop | ASP 193 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Gln 48 | 115 | B3 | GLU 26 | C-X-C chemokine receptor type 4 (R) | VdWContact |
| Val 49 | 116 | B3 | PRO 27 | C-X-C chemokine receptor type 4 (R) | VdWContact |
Interaction pattern search
Search complexes with similar interaction patterns:
