Interactions
2K04 | CXCL12_HUMAN — CXCR4 N-terminal peptide
Residue contacts: 61
SUMMARY
- Protein
- CXCL12_HUMAN View protein entry
- Organism
- Homo sapiens
- UniProt ID
- P48061 View on UniProt
- PDB ID
- 2K04 View on PDB
- Method
- Nmr
- Resolution
- -
- Date
- Oct. 28, 2008
- Reference
- 10.1126/SCISIGNAL.1160755 Open DOI
- State
- Dimer
Chain information
- Chemokine chain
- A
- Partner chain
- B
3D VIEW
INTERACTION TABLE
Download CSV| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Pro 2 | NTc.Cm7 | N-term | GLU 114 | B | Hydrophobic |
| Pro 2 | NTc.Cm7 | N-term | GLU 114 | B | VdWContact |
| Val 3 | NTc.Cm6 | N-term | ASN 111 | B | VdWContact |
| Ser 4 | NTc.Cm5 | N-term | TYR 112 | B | HBAcceptor |
| Ser 4 | NTc.Cm5 | N-term | TYR 112 | B | VdWContact |
| Ser 4 | NTc.Cm5 | N-term | ASN 111 | B | HBDonor |
| Ser 4 | NTc.Cm5 | N-term | ASN 111 | B | VdWContact |
| Pro 10 | CX.4 | CX | TYR 112 | B | Hydrophobic |
| Pro 10 | CX.4 | CX | TYR 112 | B | VdWContact |
| Pro 10 | CX.4 | CX | GLY 117 | B | VdWContact |
| Arg 12 | cxb1.1 | N-loop | GLY 117 | B | HBDonor |
| Arg 12 | cxb1.1 | N-loop | GLY 117 | B | VdWContact |
| Phe 13 | cxb1.2 | N-loop | ASP 120 | B | Hydrophobic |
| Phe 13 | cxb1.2 | N-loop | SER 118 | B | VdWContact |
| Phe 13 | cxb1.2 | N-loop | GLY 117 | B | HBDonor |
| Phe 13 | cxb1.2 | N-loop | GLY 117 | B | VdWContact |
| Phe 14 | cxb1.5 | N-loop | ASP 120 | B | VdWContact |
| Glu 15 | cxb1.6 | N-loop | ASP 120 | B | HBAcceptor |
| Glu 15 | cxb1.6 | N-loop | ASP 120 | B | VdWContact |
| Glu 15 | cxb1.6 | N-loop | SER 118 | B | VdWContact |
| Glu 15 | cxb1.6 | N-loop | GLY 119 | B | HBAcceptor |
| Glu 15 | cxb1.6 | N-loop | GLY 119 | B | VdWContact |
| Glu 15 | cxb1.6 | N-loop | TYR 121 | B | Hydrophobic |
| Glu 15 | cxb1.6 | N-loop | TYR 121 | B | VdWContact |
| Ser 16 | cxb1.8 | N-loop | ASP 122 | B | HBAcceptor |
| Ser 16 | cxb1.8 | N-loop | ASP 122 | B | VdWContact |
| Ser 16 | cxb1.8 | N-loop | TYR 121 | B | VdWContact |
| Ser 16 | cxb1.8 | N-loop | SER 123 | B | HBDonor |
| Ser 16 | cxb1.8 | N-loop | SER 123 | B | VdWContact |
| His 17 | cxb1.10 | N-loop | ASP 122 | B | Hydrophobic |
| His 17 | cxb1.10 | N-loop | ASP 122 | B | VdWContact |
| His 17 | cxb1.10 | N-loop | SER 123 | B | VdWContact |
| Val 18 | cxb1.11 | N-loop | TYR 121 | B | Hydrophobic |
| Val 18 | cxb1.11 | N-loop | TYR 121 | B | VdWContact |
| Ala 19 | cxb1.14 | N-loop | TYR 121 | B | Hydrophobic |
| Lys 27 | B1.6 | B1 | TYR 112 | B | HBDonor |
| Lys 27 | B1.6 | B1 | TYR 112 | B | VdWContact |
| Ile 28 | B1.7 | B1 | TYR 107 | B | HBAcceptor |
| Ile 28 | B1.7 | B1 | TYR 107 | B | VdWContact |
| Leu 29 | b1b2.4 | 30s-loop | TYR 112 | B | Hydrophobic |
| Leu 29 | b1b2.4 | 30s-loop | TYR 112 | B | VdWContact |
| Leu 29 | b1b2.4 | 30s-loop | TYR 107 | B | VdWContact |
| Asn 30 | b1b2.7 | 30s-loop | TYR 107 | B | Hydrophobic |
| Asn 30 | b1b2.7 | 30s-loop | TYR 107 | B | VdWContact |
| Asn 30 | b1b2.7 | 30s-loop | ILE 106 | B | VdWContact |
| Thr 31 | b1b2.8 | 30s-loop | TYR 112 | B | Hydrophobic |
| Val 39 | B2.3 | B2 | TYR 112 | B | Hydrophobic |
| Arg 41 | B2.5 | B2 | GLU 115 | B | Cationic |
| Arg 47 | b2b3.12 | 40s-loop | MET 116 | B | Hydrophobic |
| Arg 47 | b2b3.12 | 40s-loop | MET 116 | B | VdWContact |
| Gln 48 | B3.1 | B3 | GLU 115 | B | HBDonor |
| Gln 48 | B3.1 | B3 | GLU 115 | B | VdWContact |
| Cys 50 | B3.3 | B3 | SER 118 | B | HBDonor |
| Cys 50 | B3.3 | B3 | SER 118 | B | VdWContact |
| Lys 54 | b3h.3 | 50s-loop | LYS 125 | B | VdWContact |
| Lys 54 | b3h.3 | 50s-loop | PRO 127 | B | VdWContact |
| Lys 54 | b3h.3 | 50s-loop | GLU 126 | B | Hydrophobic |
| Lys 54 | b3h.3 | 50s-loop | GLU 126 | B | VdWContact |
| Lys 56 | H.1 | Helix | GLU 132 | B | HBDonor |
| Lys 56 | H.1 | Helix | GLU 132 | B | VdWContact |
| Gln 59 | H.4 | Helix | PRO 127 | B | Hydrophobic |
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