Interactions for 2K05 — Binding Partner: CXCL12
Structure details
- PDB ID: 2K05 open_in_new
- Protein: CXCL12_HUMAN
- Organism: Homo sapiens
- UniProt ID: P48061 open_in_new
- Method: Nmr
- Resolution:
- Date: Oct. 28, 2008
- Reference: 10.1126/SCISIGNAL.1160755 open_in_new
- State: Dimer
- Chemokine Chain: C
- Partner Chain: A
Chemokine diagram
Interactions for this Binding Partner
Download list as CSV
| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Val 203 | NTc.Cm6 | N-term | LYS 24 | A | Hydrophobic |
| His 225 | B1.4 | B1 | LEU 29 | A | Hydrophobic |
| His 225 | B1.4 | B1 | LEU 29 | A | VdWContact |
| His 225 | B1.4 | B1 | ILE 28 | A | VdWContact |
| His 225 | B1.4 | B1 | LYS 27 | A | Hydrophobic |
| Leu 226 | B1.5 | B1 | ILE 28 | A | Hydrophobic |
| Leu 226 | B1.5 | B1 | ILE 28 | A | HBAcceptor |
| Leu 226 | B1.5 | B1 | ILE 28 | A | HBDonor |
| Leu 226 | B1.5 | B1 | ILE 28 | A | VdWContact |
| Lys 227 | B1.6 | B1 | HIS 25 | A | Hydrophobic |
| Lys 227 | B1.6 | B1 | LEU 26 | A | VdWContact |
| Lys 227 | B1.6 | B1 | LYS 27 | A | Hydrophobic |
| Lys 227 | B1.6 | B1 | LYS 27 | A | VdWContact |
| Ile 228 | B1.7 | B1 | HIS 25 | A | VdWContact |
| Ile 228 | B1.7 | B1 | LEU 26 | A | HBAcceptor |
| Ile 228 | B1.7 | B1 | LEU 26 | A | HBDonor |
| Ile 228 | B1.7 | B1 | LEU 26 | A | VdWContact |
| Ile 228 | B1.7 | B1 | TYR 61 | A | Hydrophobic |
| Ile 228 | B1.7 | B1 | TYR 61 | A | VdWContact |
| Ile 228 | B1.7 | B1 | ILE 28 | A | Hydrophobic |
| Leu 229 | b1b2.4 | 30s-loop | HIS 25 | A | Hydrophobic |
| Leu 229 | b1b2.4 | 30s-loop | HIS 25 | A | VdWContact |
| Asn 230 | b1b2.7 | 30s-loop | LYS 64 | A | VdWContact |
| Ala 235 | b1b2.14 | 30s-loop | LYS 68 | A | Hydrophobic |
| Ala 235 | b1b2.14 | 30s-loop | LYS 68 | A | HBAcceptor |
| Ala 235 | b1b2.14 | 30s-loop | LYS 68 | A | VdWContact |
| Leu 236 | b1b2.16 | 30s-loop | CYS 65 | A | Hydrophobic |
| Leu 236 | b1b2.16 | 30s-loop | CYS 65 | A | VdWContact |
| Pro 253 | b3h.2 | 50s-loop | CYS 65 | A | VdWContact |
| Gln 259 | H.4 | Helix | LEU 66 | A | Hydrophobic |
| Gln 259 | H.4 | Helix | LEU 66 | A | HBDonor |
| Gln 259 | H.4 | Helix | LEU 66 | A | VdWContact |
| Tyr 261 | H.6 | Helix | ASN 30 | A | VdWContact |
| Tyr 261 | H.6 | Helix | ILE 28 | A | Hydrophobic |
| Tyr 261 | H.6 | Helix | ILE 28 | A | VdWContact |
| Leu 262 | H.7 | Helix | LEU 62 | A | Hydrophobic |
| Leu 262 | H.7 | Helix | CYS 65 | A | Hydrophobic |
| Leu 262 | H.7 | Helix | LEU 66 | A | Hydrophobic |
| Leu 262 | H.7 | Helix | LEU 66 | A | VdWContact |
| Ala 265 | H.10 | Helix | LEU 62 | A | Hydrophobic |
| Ala 265 | H.10 | Helix | PRO 53 | A | VdWContact |
| Ala 265 | H.10 | Helix | CYS 36 | A | Hydrophobic |
| Ala 265 | H.10 | Helix | CYS 36 | A | VdWContact |
| Leu 266 | CT.1 | C-term | GLN 59 | A | Hydrophobic |
| Leu 266 | CT.1 | C-term | GLN 59 | A | VdWContact |
| Leu 266 | CT.1 | C-term | LEU 62 | A | Hydrophobic |
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