Interactions

2X6L | CCL4_HUMAN — CCL4

Residue contacts: 108
SUMMARY
Protein
CCL4_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
P13236 View on UniProt
PDB ID
2X6L View on PDB
Method
X-ray
Resolution
2.6 Å
Date
Nov. 3, 2010
Reference
10.1038/EMBOJ.2010.256 Open DOI
State
Oligomer
Chain information
Chemokine chain
B
Partner chain
A,C,D,E
3D VIEW
Powered by NGL viewer
INTERACTION TABLE
Download CSV
Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Ser 5 NTc.Cm6 N-term SER 32 C VdWContact
Ser 5 NTc.Cm6 N-term GLU 30 C VdWContact
Ser 5 NTc.Cm6 N-term ARG 18 D HBAcceptor
Ser 5 NTc.Cm6 N-term ARG 18 D VdWContact
Asp 6 NTc.Cm5 N-term SER 32 C HBAcceptor
Asp 6 NTc.Cm5 N-term SER 32 C VdWContact
Asp 6 NTc.Cm5 N-term SER 14 D VdWContact
Asp 6 NTc.Cm5 N-term SER 33 C HBAcceptor
Asp 6 NTc.Cm5 N-term SER 33 C VdWContact
Asp 6 NTc.Cm5 N-term CYS 51 D HBAcceptor
Asp 6 NTc.Cm5 N-term CYS 51 D VdWContact
Asp 6 NTc.Cm5 N-term ARG 18 D Anionic
Pro 7 NTc.Cm4 N-term GLN 49 D VdWContact
Pro 7 NTc.Cm4 N-term CYS 51 D VdWContact
Pro 8 NTc.Cm3 N-term GLN 49 D Hydrophobic
Pro 8 NTc.Cm3 N-term ALA 10 D Hydrophobic
Pro 8 NTc.Cm3 N-term VAL 41 D Hydrophobic
Pro 8 NTc.Cm3 N-term CYS 51 D VdWContact
Thr 9 NTc.Cm2 N-term PHE 13 D Hydrophobic
Thr 9 NTc.Cm2 N-term PHE 13 D VdWContact
Thr 9 NTc.Cm2 N-term CYS 11 D HBAcceptor
Thr 9 NTc.Cm2 N-term CYS 11 D HBDonor
Thr 9 NTc.Cm2 N-term CYS 11 D VdWContact
Ala 10 NTc.Cm1 N-term PRO 8 D Hydrophobic
Ala 10 NTc.Cm1 N-term PRO 8 D VdWContact
Cys 11 CX.1 CX PHE 13 D VdWContact
Cys 11 CX.1 CX THR 9 D HBAcceptor
Cys 11 CX.1 CX THR 9 D HBDonor
Cys 11 CX.1 CX THR 9 D VdWContact
Cys 11 CX.1 CX PRO 8 D VdWContact
Phe 13 cxb1.1 N-loop THR 9 D Hydrophobic
Phe 13 cxb1.1 N-loop THR 9 D VdWContact
Phe 13 cxb1.1 N-loop LEU 34 D Hydrophobic
Tyr 15 cxb1.5 N-loop SER 33 A HBAcceptor
Tyr 15 cxb1.5 N-loop SER 33 A VdWContact
Arg 18 cxb1.8 N-loop GLU 30 A HBDonor
Arg 18 cxb1.8 N-loop GLU 30 A Cationic
Arg 18 cxb1.8 N-loop GLU 30 A VdWContact
Arg 18 cxb1.8 N-loop THR 31 A HBDonor
Arg 18 cxb1.8 N-loop THR 31 A VdWContact
Arg 18 cxb1.8 N-loop PRO 38 A VdWContact
Arg 18 cxb1.8 N-loop ALA 39 A VdWContact
Pro 21 cxb1.14 N-loop TYR 64 A Hydrophobic
Phe 24 B1.1 B1 TYR 64 A Hydrophobic
Phe 24 B1.1 B1 TYR 64 A VdWContact
Phe 24 B1.1 B1 GLU 67 A Hydrophobic
Phe 24 B1.1 B1 GLU 67 A VdWContact
Phe 24 B1.1 B1 LEU 68 A Hydrophobic
Phe 24 B1.1 B1 LEU 68 A VdWContact
Phe 24 B1.1 B1 VAL 63 A Hydrophobic
Asp 27 B1.4 B1 ARG 46 E HBAcceptor
Asp 27 B1.4 B1 ARG 46 E Anionic
Asp 27 B1.4 B1 ARG 46 E VdWContact
Asp 27 B1.4 B1 LYS 48 E Anionic
Tyr 28 B1.5 B1 LYS 48 E HBAcceptor
Tyr 28 B1.5 B1 LYS 48 E VdWContact
Glu 30 B1.7 B1 SER 5 C VdWContact
Glu 30 B1.7 B1 ARG 18 E Anionic
Glu 30 B1.7 B1 ARG 18 E VdWContact
Thr 31 b1b2.4 30s-loop ARG 18 E VdWContact
Ser 32 b1b2.6 30s-loop SER 5 C VdWContact
Ser 33 b1b2.9 30s-loop TYR 15 E HBDonor
Ser 33 b1b2.9 30s-loop TYR 15 E VdWContact
Ser 33 b1b2.9 30s-loop ASP 6 C HBDonor
Ser 33 b1b2.9 30s-loop ASP 6 C VdWContact
Leu 34 b1b2.10 30s-loop PHE 13 D Hydrophobic
Pro 38 b1b2.16 30s-loop ARG 18 E VdWContact
Ala 39 B2.1 B2 ARG 18 E VdWContact
Val 41 B2.3 B2 PRO 8 D Hydrophobic
Lys 45 b2b3.2 40s-loop GLU 67 A Hydrophobic
Lys 45 b2b3.2 40s-loop GLU 67 A VdWContact
Lys 45 b2b3.2 40s-loop LEU 68 A Hydrophobic
Lys 45 b2b3.2 40s-loop LEU 68 A HBDonor
Lys 45 b2b3.2 40s-loop LEU 68 A VdWContact
Arg 46 b2b3.4 40s-loop GLU 67 A HBDonor
Arg 46 b2b3.4 40s-loop GLU 67 A VdWContact
Arg 46 b2b3.4 40s-loop LEU 66 A HBDonor
Arg 46 b2b3.4 40s-loop LEU 66 A VdWContact
Arg 46 b2b3.4 40s-loop ASP 27 A HBDonor
Arg 46 b2b3.4 40s-loop ASP 27 A Cationic
Arg 46 b2b3.4 40s-loop ASP 27 A VdWContact
Arg 46 b2b3.4 40s-loop VAL 26 A HBDonor
Lys 48 b2b3.12 40s-loop GLU 67 A Cationic
Lys 48 b2b3.12 40s-loop TYR 28 A CationPi
Lys 48 b2b3.12 40s-loop TYR 28 A VdWContact
Lys 48 b2b3.12 40s-loop ASP 27 A HBDonor
Lys 48 b2b3.12 40s-loop ASP 27 A Cationic
Lys 48 b2b3.12 40s-loop ASP 27 A VdWContact
Gln 49 B3.1 B3 PRO 8 D Hydrophobic
Gln 49 B3.1 B3 PRO 7 D VdWContact
Cys 51 B3.3 B3 ASP 6 D HBDonor
Cys 51 B3.3 B3 ASP 6 D VdWContact
Val 63 H.7 Helix PHE 24 E Hydrophobic
Tyr 64 H.8 Helix ASN 23 E VdWContact
Tyr 64 H.8 Helix PRO 21 E Hydrophobic
Tyr 64 H.8 Helix PHE 24 E Hydrophobic
Glu 67 CT.1 C-term THR 44 E HBAcceptor
Glu 67 CT.1 C-term THR 44 E VdWContact
Glu 67 CT.1 C-term LYS 45 E Hydrophobic
Glu 67 CT.1 C-term ARG 46 E HBAcceptor
Glu 67 CT.1 C-term ARG 46 E VdWContact
Glu 67 CT.1 C-term PHE 24 E Hydrophobic
Glu 67 CT.1 C-term PHE 24 E VdWContact
Leu 68 CT.2 C-term ASN 23 E VdWContact
Leu 68 CT.2 C-term LYS 45 E Hydrophobic
Leu 68 CT.2 C-term LYS 45 E HBAcceptor
Leu 68 CT.2 C-term LYS 45 E VdWContact
Leu 68 CT.2 C-term PHE 24 E Hydrophobic
CHEMOKINE DIAGRAM
T S S L C S Q P 30s-loop K R S K 40s-loop D P S E 50s-loopC-term S D P P T A C C F S Y T A R K L P R N N-term E Y Y D V V F A V V F Q T A C V Q S W V Q E Y V Y D L E L N
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical