Interactions for 6WZM — Binding Partner: LY3041658
Structure details
- PDB ID: 6WZM open_in_new
- Protein: CXCL8_HUMAN
- Organism: Homo sapiens
- UniProt ID: P10145 open_in_new
- Method: X-ray
- Resolution: 2.28 Å
- Date: Nov. 25, 2020
- Reference: 10.1080/19420862.2020.1831880 open_in_new
- State: Dimer
- Chemokine Chain: E
- Partner Chain: A,B
Chemokine diagram
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Interactions for this Binding Partner
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Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
---|---|---|---|---|---|
Leu 5 | 61 | N-term | TRP 94 | B | HBAcceptor |
Leu 5 | 61 | N-term | TRP 94 | B | VdWContact |
Leu 5 | 61 | N-term | GLU 93 | B | Hydrophobic |
Leu 5 | 61 | N-term | GLU 93 | B | VdWContact |
Arg 6 | 62 | N-term | TRP 94 | B | Hydrophobic |
Arg 6 | 62 | N-term | GLU 99 | A | HBDonor |
Arg 6 | 62 | N-term | GLU 99 | A | Cationic |
Arg 6 | 62 | N-term | GLU 99 | A | VdWContact |
Arg 6 | 62 | N-term | TYR 110 | A | Hydrophobic |
Arg 6 | 62 | N-term | TYR 110 | A | CationPi |
Arg 6 | 62 | N-term | TYR 110 | A | VdWContact |
Arg 6 | 62 | N-term | ASN 91 | B | HBDonor |
Arg 6 | 62 | N-term | ASN 91 | B | VdWContact |
Cys 7 | 63 | CX | TRP 94 | B | Hydrophobic |
Cys 7 | 63 | CX | TRP 94 | B | VdWContact |
Cys 7 | 63 | CX | TRP 33 | A | Hydrophobic |
Gln 8 | 66 | CX | PRO 106 | A | Hydrophobic |
Ile 10 | 68 | N-loop | SER 52 | A | VdWContact |
Ile 10 | 68 | N-loop | TRP 33 | A | Hydrophobic |
Ile 10 | 68 | N-loop | TYR 32 | A | VdWContact |
Ile 10 | 68 | N-loop | TYR 102 | A | Hydrophobic |
Ile 10 | 68 | N-loop | TYR 102 | A | VdWContact |
Lys 11 | 69 | N-loop | SER 103 | A | VdWContact |
Lys 11 | 69 | N-loop | GLU 28 | A | Cationic |
Lys 11 | 69 | N-loop | THR 30 | A | HBDonor |
Lys 11 | 69 | N-loop | THR 30 | A | VdWContact |
Lys 11 | 69 | N-loop | TYR 104 | A | Hydrophobic |
Tyr 13 | 71 | N-loop | TYR 104 | A | Hydrophobic |
His 33 | 94 | 30s-loop | TRP 94 | B | HBDonor |
His 33 | 94 | 30s-loop | TRP 94 | B | VdWContact |
Ala 35 | 96 | 30s-loop | ASN 59 | A | HBDonor |
Ala 35 | 96 | 30s-loop | ASN 59 | A | VdWContact |
Asn 36 | 97 | 30s-loop | SER 57 | A | VdWContact |
Ile 40 | 102 | B2 | PRO 106 | A | Hydrophobic |
Ile 40 | 102 | B2 | PRO 106 | A | VdWContact |
Arg 47 | 114 | 40s-loop | TYR 105 | A | Hydrophobic |
Arg 47 | 114 | 40s-loop | TYR 105 | A | VdWContact |
Glu 48 | 115 | B3 | PRO 106 | A | Hydrophobic |
Glu 48 | 115 | B3 | PRO 106 | A | VdWContact |
Glu 48 | 115 | B3 | TYR 105 | A | VdWContact |
Leu 49 | 116 | B3 | TYR 104 | A | Hydrophobic |
Leu 49 | 116 | B3 | TYR 105 | A | Hydrophobic |
Cys 50 | 117 | B3 | TYR 104 | A | Hydrophobic |
Cys 50 | 117 | B3 | TYR 104 | A | HBDonor |
Cys 50 | 117 | B3 | TYR 104 | A | VdWContact |