Interactions for 2NZ1 — Binding Partner: M3 protein
Structure details
- PDB ID: 2NZ1 open_in_new
- Protein: CCL2_HUMAN
- Organism: Homo sapiens
- UniProt ID: P13500 open_in_new
- Method: X-ray
- Resolution: 2.5 Å
- Date: Dec. 25, 2007
- Reference: 10.1084/JEM.20071677 open_in_new
- State: Monomer
- Chemokine Chain: E
- Partner Chain: A,B
Chemokine diagram
Interactions for this Binding Partner
Download list as CSV
| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Val 9 | NTc.Cm2 | N-term | ALA 275 | B | Hydrophobic |
| Val 9 | NTc.Cm2 | N-term | ALA 275 | B | HBAcceptor |
| Val 9 | NTc.Cm2 | N-term | ALA 275 | B | VdWContact |
| Thr 10 | NTc.Cm1 | N-term | LEU 273 | B | VdWContact |
| Cys 11 | CX.1 | CX | LEU 273 | B | HBAcceptor |
| Cys 11 | CX.1 | CX | LEU 273 | B | HBDonor |
| Cys 11 | CX.1 | CX | LEU 273 | B | VdWContact |
| Cys 11 | CX.1 | CX | PRO 272 | B | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | TYR 266 | B | Hydrophobic |
| Tyr 13 | cxb1.1 | N-loop | TYR 266 | B | PiStacking |
| Tyr 13 | cxb1.1 | N-loop | PRO 356 | B | Hydrophobic |
| Tyr 13 | cxb1.1 | N-loop | PRO 356 | B | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | ALA 275 | B | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | LEU 273 | B | Hydrophobic |
| Asn 14 | cxb1.2 | N-loop | SER 269 | B | HBDonor |
| Asn 14 | cxb1.2 | N-loop | SER 269 | B | VdWContact |
| Asn 14 | cxb1.2 | N-loop | TYR 266 | B | HBDonor |
| Asn 14 | cxb1.2 | N-loop | TYR 266 | B | VdWContact |
| Asn 14 | cxb1.2 | N-loop | PRO 360 | B | VdWContact |
| Asn 14 | cxb1.2 | N-loop | VAL 270 | B | Hydrophobic |
| Asn 14 | cxb1.2 | N-loop | VAL 270 | B | VdWContact |
| Asn 17 | cxb1.7 | N-loop | TYR 127 | A | Hydrophobic |
| Asn 17 | cxb1.7 | N-loop | TYR 127 | A | VdWContact |
| Arg 18 | cxb1.8 | N-loop | GLU 129 | A | HBDonor |
| Arg 18 | cxb1.8 | N-loop | GLU 129 | A | Cationic |
| Arg 18 | cxb1.8 | N-loop | GLU 129 | A | VdWContact |
| Arg 18 | cxb1.8 | N-loop | THR 172 | A | Hydrophobic |
| Arg 18 | cxb1.8 | N-loop | TYR 127 | A | Hydrophobic |
| Lys 19 | cxb1.10 | N-loop | TYR 125 | A | Hydrophobic |
| Lys 19 | cxb1.10 | N-loop | TYR 125 | A | HBDonor |
| Lys 19 | cxb1.10 | N-loop | TYR 125 | A | VdWContact |
| Lys 19 | cxb1.10 | N-loop | LEU 174 | A | Hydrophobic |
| Lys 19 | cxb1.10 | N-loop | LEU 174 | A | VdWContact |
| Ile 20 | cxb1.11 | N-loop | LEU 82 | A | Hydrophobic |
| Ile 20 | cxb1.11 | N-loop | LEU 82 | A | VdWContact |
| Ser 21 | cxb1.14 | N-loop | LEU 82 | A | HBDonor |
| Ser 21 | cxb1.14 | N-loop | LEU 82 | A | VdWContact |
| Arg 24 | B1.1 | B1 | GLU 80 | A | HBDonor |
| Arg 24 | B1.1 | B1 | GLU 80 | A | VdWContact |
| Lys 35 | b1b2.10 | 30s-loop | ALA 275 | B | Hydrophobic |
| Lys 38 | b1b2.14 | 30s-loop | THR 357 | B | HBDonor |
| Lys 38 | b1b2.14 | 30s-loop | THR 357 | B | VdWContact |
| Ile 42 | B2.3 | B2 | PRO 272 | B | Hydrophobic |
| Thr 45 | B2.6 | B2 | LEU 82 | A | Hydrophobic |
| Lys 49 | b2b3.12 | 40s-loop | GLU 81 | A | HBDonor |
| Lys 49 | b2b3.12 | 40s-loop | GLU 81 | A | Cationic |
| Lys 49 | b2b3.12 | 40s-loop | GLU 81 | A | VdWContact |
| Glu 50 | B3.1 | B3 | SER 271 | B | HBAcceptor |
| Glu 50 | B3.1 | B3 | SER 271 | B | VdWContact |
| Glu 50 | B3.1 | B3 | PRO 272 | B | Hydrophobic |
| Ile 51 | B3.2 | B3 | VAL 270 | B | Hydrophobic |
| Ile 51 | B3.2 | B3 | LEU 82 | A | Hydrophobic |
| Ile 51 | B3.2 | B3 | LEU 82 | A | VdWContact |
| Cys 52 | B3.3 | B3 | VAL 270 | B | HBDonor |
| Cys 52 | B3.3 | B3 | VAL 270 | B | VdWContact |
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