Interactions for 4DN4 — Binding Partner: CNTO888

Structure details

PDB ID: 4DN4 open_in_new
Protein: CCL2_HUMAN
Organism: Homo sapiens
UniProt ID: P13500 open_in_new

Method: X-ray
Resolution: 2.8 Å
Date: Oct. 3, 2012
Reference: 10.1016/J.MOLIMM.2012.03.022 open_in_new
State: Monomer

Chemokine Chain: M
Partner Chain: H,L

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Interactions for this Binding Partner

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Chemokine Residue	Generic Number	Segment	Partner Residue	Partner Chain	Interaction Type
Arg 18	cxb1.8	N-loop	GLU 105	H	HBDonor
Arg 18	cxb1.8	N-loop	GLU 105	H	Cationic
Arg 18	cxb1.8	N-loop	GLU 105	H	VdWContact
Arg 18	cxb1.8	N-loop	ASP 51	L	HBDonor
Arg 18	cxb1.8	N-loop	ASP 51	L	Cationic
Arg 18	cxb1.8	N-loop	ASP 51	L	VdWContact
Arg 18	cxb1.8	N-loop	TYR 50	L	VdWContact
Arg 18	cxb1.8	N-loop	TYR 103	H	Hydrophobic
Arg 18	cxb1.8	N-loop	TYR 103	H	HBAcceptor
Arg 18	cxb1.8	N-loop	TYR 103	H	CationPi
Arg 18	cxb1.8	N-loop	TYR 103	H	VdWContact
Lys 19	cxb1.10	N-loop	ASP 31	L	HBDonor
Lys 19	cxb1.10	N-loop	ASP 31	L	Cationic
Lys 19	cxb1.10	N-loop	ASP 31	L	VdWContact
Ile 20	cxb1.11	N-loop	ILE 102	H	Hydrophobic
Ile 20	cxb1.11	N-loop	TYR 103	H	Hydrophobic
Ser 21	cxb1.14	N-loop	TYR 33	L	HBDonor
Ser 21	cxb1.14	N-loop	TYR 33	L	VdWContact
Ser 21	cxb1.14	N-loop	ASP 31	L	HBDonor
Ser 21	cxb1.14	N-loop	ASP 31	L	VdWContact
Arg 24	B1.1	B1	TYR 92	L	HBDonor
Arg 24	B1.1	B1	TYR 92	L	VdWContact
Arg 24	B1.1	B1	TYR 33	L	Hydrophobic
Arg 24	B1.1	B1	ILE 102	H	Hydrophobic
Arg 24	B1.1	B1	ILE 102	H	VdWContact
Arg 24	B1.1	B1	LEU 95	L	VdWContact
Arg 24	B1.1	B1	GLY 101	H	HBDonor
Arg 24	B1.1	B1	GLY 101	H	VdWContact
Arg 24	B1.1	B1	TYR 103	H	HBDonor
Arg 24	B1.1	B1	TYR 103	H	VdWContact
Arg 24	B1.1	B1	ILE 93	L	HBDonor
Arg 24	B1.1	B1	ILE 93	L	VdWContact
Thr 45	B2.6	B2	ILE 102	H	Hydrophobic
Thr 45	B2.6	B2	ILE 102	H	VdWContact
Ile 46	b2b3.2	40s-loop	PHE 55	H	VdWContact
Val 47	b2b3.4	40s-loop	ILE 54	H	Hydrophobic
Val 47	b2b3.4	40s-loop	PHE 55	H	Hydrophobic
Val 47	b2b3.4	40s-loop	ILE 52	H	Hydrophobic
Val 47	b2b3.4	40s-loop	GLY 101	H	VdWContact
Ala 48	b2b3.11	40s-loop	ILE 54	H	Hydrophobic
Lys 49	b2b3.12	40s-loop	SER 31	H	HBDonor
Lys 49	b2b3.12	40s-loop	SER 31	H	VdWContact
Lys 49	b2b3.12	40s-loop	ASP 100	H	HBDonor
Lys 49	b2b3.12	40s-loop	ASP 100	H	Cationic
Lys 49	b2b3.12	40s-loop	ASP 100	H	VdWContact
Ile 51	B3.2	B3	ILE 102	H	Hydrophobic

Interactions for 4DN4 — Binding Partner: CNTO888

Structure details

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Chemokine diagram

Interactions for this Binding Partner

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