Interactions for 4R9Y — Binding Partner: CXCL4
Structure details
- PDB ID: 4R9Y open_in_new
- Protein: CXCL4_HUMAN
- Organism: Homo sapiens
- UniProt ID: P02776 open_in_new
- Method: X-ray
- Resolution: 4.11 Å
- Date: Dec. 16, 2015
- Reference: 10.1038/NCOMMS9277 open_in_new
- State: Tetramer
- Chemokine Chain: D
- Partner Chain: A,B,C
Chemokine diagram
Interactions for this Binding Partner
Download list as CSV
| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Asp 7 | NTc.Cm3 | N-term | LYS 14 | B | Hydrophobic |
| Asp 7 | NTc.Cm3 | N-term | LYS 14 | B | VdWContact |
| Asp 7 | NTc.Cm3 | N-term | CYS 52 | B | HBAcceptor |
| Asp 7 | NTc.Cm3 | N-term | CYS 52 | B | VdWContact |
| Asp 7 | NTc.Cm3 | N-term | VAL 13 | B | Hydrophobic |
| Asp 7 | NTc.Cm3 | N-term | VAL 13 | B | VdWContact |
| Leu 8 | NTc.Cm2 | N-term | LYS 50 | B | Hydrophobic |
| Leu 8 | NTc.Cm2 | N-term | LYS 50 | B | VdWContact |
| Leu 8 | NTc.Cm2 | N-term | VAL 13 | B | VdWContact |
| Leu 8 | NTc.Cm2 | N-term | LEU 11 | B | VdWContact |
| Gln 9 | NTc.Cm1 | N-term | VAL 13 | B | Hydrophobic |
| Gln 9 | NTc.Cm1 | N-term | VAL 13 | B | VdWContact |
| Gln 9 | NTc.Cm1 | N-term | CYS 10 | B | VdWContact |
| Gln 9 | NTc.Cm1 | N-term | LEU 11 | B | VdWContact |
| Gln 9 | NTc.Cm1 | N-term | GLN 9 | B | VdWContact |
| Leu 11 | CX.4 | CX | LEU 11 | B | Hydrophobic |
| Leu 11 | CX.4 | CX | LEU 11 | B | VdWContact |
| Leu 11 | CX.4 | CX | GLN 9 | B | HBAcceptor |
| Leu 11 | CX.4 | CX | GLN 9 | B | VdWContact |
| Val 13 | cxb1.1 | N-loop | ASP 7 | B | VdWContact |
| Val 13 | cxb1.1 | N-loop | GLN 9 | B | Hydrophobic |
| Lys 14 | cxb1.2 | N-loop | ASP 7 | B | Hydrophobic |
| Lys 14 | cxb1.2 | N-loop | ASP 7 | B | Cationic |
| Lys 14 | cxb1.2 | N-loop | ASP 7 | B | VdWContact |
| Leu 27 | B1.5 | B1 | GLU 28 | C | VdWContact |
| Leu 27 | B1.5 | B1 | VAL 29 | C | HBAcceptor |
| Leu 27 | B1.5 | B1 | VAL 29 | C | HBDonor |
| Leu 27 | B1.5 | B1 | VAL 29 | C | VdWContact |
| Glu 28 | B1.6 | B1 | GLU 28 | C | Hydrophobic |
| Glu 28 | B1.6 | B1 | GLU 28 | C | VdWContact |
| Val 29 | B1.7 | B1 | SER 26 | C | VdWContact |
| Val 29 | B1.7 | B1 | LEU 27 | C | HBAcceptor |
| Val 29 | B1.7 | B1 | LEU 27 | C | HBDonor |
| Val 29 | B1.7 | B1 | LEU 27 | C | VdWContact |
| Lys 31 | b1b2.6 | 30s-loop | LEU 67 | C | Hydrophobic |
| Lys 31 | b1b2.6 | 30s-loop | THR 25 | C | Hydrophobic |
| Lys 31 | b1b2.6 | 30s-loop | THR 25 | C | VdWContact |
| Lys 46 | b2b3.2 | 40s-loop | LYS 31 | C | VdWContact |
| Asn 47 | b2b3.4 | 40s-loop | ASN 47 | A | VdWContact |
| Cys 52 | B3.3 | B3 | LEU 8 | B | VdWContact |
| Leu 55 | b3h.2 | 50s-loop | LEU 68 | C | Hydrophobic |
| Lys 61 | H.4 | Helix | LYS 65 | C | VdWContact |
| Leu 67 | H.10 | Helix | LYS 31 | C | Hydrophobic |
| Leu 68 | CT.1 | C-term | LEU 55 | C | Hydrophobic |
| Leu 68 | CT.1 | C-term | LEU 55 | C | VdWContact |
| Leu 68 | CT.1 | C-term | ALA 39 | C | Hydrophobic |
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