Interactions for 4RWS — Binding Partner: CXCR4
Structure details
- PDB ID: 4RWS open_in_new
- Protein: CXCL2_HHV8P
- Organism: Human herpesvirus 8 type P (isolate GK18)
- UniProt ID: Q98157 open_in_new
- Method: X-ray
- Resolution: 3.1 Å
- Date: Feb. 11, 2015
- Reference: 10.1126/SCIENCE.1261064 open_in_new
- State: Monomer
- Chemokine Chain: C
- Partner Chain: A
Chemokine diagram
Interactions for this Binding Partner
Download list as CSV
| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Leu 1 | NTc.Cm10 | N-term | HIS 113 | A | Hydrophobic |
| Leu 1 | NTc.Cm10 | N-term | HIS 113 | A | VdWContact |
| Leu 1 | NTc.Cm10 | N-term | VAL 112 | A | Hydrophobic |
| Leu 1 | NTc.Cm10 | N-term | ASP 97 | A | Hydrophobic |
| Leu 1 | NTc.Cm10 | N-term | ASP 97 | A | VdWContact |
| Leu 1 | NTc.Cm10 | N-term | TRP 94 | A | Hydrophobic |
| Leu 1 | NTc.Cm10 | N-term | TRP 102 | A | Hydrophobic |
| Gly 2 | NTc.Cm9 | N-term | GLU 288 | A | VdWContact |
| Ala 3 | NTc.Cm8 | N-term | GLU 288 | A | HBDonor |
| Ala 3 | NTc.Cm8 | N-term | GLU 288 | A | VdWContact |
| Ala 3 | NTc.Cm8 | N-term | HIS 281 | A | VdWContact |
| Ser 4 | NTc.Cm7 | N-term | ASP 97 | A | HBDonor |
| Ser 4 | NTc.Cm7 | N-term | ASP 97 | A | VdWContact |
| Trp 5 | NTc.Cm6 | N-term | CYS 187 | A | Hydrophobic |
| Trp 5 | NTc.Cm6 | N-term | CYS 187 | A | VdWContact |
| His 6 | NTc.Cm5 | N-term | ASP 262 | A | HBDonor |
| His 6 | NTc.Cm5 | N-term | ASP 262 | A | VdWContact |
| His 6 | NTc.Cm5 | N-term | ILE 284 | A | Hydrophobic |
| His 6 | NTc.Cm5 | N-term | HIS 281 | A | Hydrophobic |
| His 6 | NTc.Cm5 | N-term | HIS 281 | A | HBAcceptor |
| His 6 | NTc.Cm5 | N-term | HIS 281 | A | VdWContact |
| Arg 7 | NTc.Cm4 | N-term | GLU 277 | A | Cationic |
| Arg 7 | NTc.Cm4 | N-term | ARG 30 | A | VdWContact |
| Arg 7 | NTc.Cm4 | N-term | ASP 262 | A | HBDonor |
| Arg 7 | NTc.Cm4 | N-term | ASP 262 | A | Cationic |
| Arg 7 | NTc.Cm4 | N-term | ASP 262 | A | VdWContact |
| Pro 8 | NTc.Cm3 | N-term | ILE 185 | A | Hydrophobic |
| Asp 9 | NTc.Cm2 | N-term | ALA 180 | A | VdWContact |
| Asp 9 | NTc.Cm2 | N-term | ARG 30 | A | HBAcceptor |
| Asp 9 | NTc.Cm2 | N-term | ARG 30 | A | VdWContact |
| Asp 9 | NTc.Cm2 | N-term | ASP 181 | A | Hydrophobic |
| Asp 9 | NTc.Cm2 | N-term | ASP 181 | A | VdWContact |
| Lys 10 | NTc.Cm1 | N-term | ASP 181 | A | Cationic |
| Lys 10 | NTc.Cm1 | N-term | ASP 182 | A | Cationic |
| Lys 10 | NTc.Cm1 | N-term | PHE 29 | A | Hydrophobic |
| Lys 10 | NTc.Cm1 | N-term | PHE 29 | A | VdWContact |
| Lys 10 | NTc.Cm1 | N-term | CYS 28 | A | VdWContact |
| Cys 11 | CX.1 | CX | ARG 30 | A | Anionic |
| Cys 11 | CX.1 | CX | ARG 30 | A | VdWContact |
| Cys 11 | CX.1 | CX | CYS 28 | A | HBAcceptor |
| Cys 11 | CX.1 | CX | CYS 28 | A | VdWContact |
| Leu 13 | cxb1.1 | N-loop | GLU 277 | A | VdWContact |
| Leu 13 | cxb1.1 | N-loop | CYS 274 | A | Hydrophobic |
| Leu 13 | cxb1.1 | N-loop | CYS 28 | A | Hydrophobic |
| Gly 14 | cxb1.2 | N-loop | LYS 25 | A | VdWContact |
| Gln 16 | cxb1.6 | N-loop | MET 24 | A | VdWContact |
| Gln 16 | cxb1.6 | N-loop | LYS 25 | A | Hydrophobic |
| Gln 16 | cxb1.6 | N-loop | LYS 25 | A | HBAcceptor |
| Gln 16 | cxb1.6 | N-loop | LYS 25 | A | VdWContact |
| Gln 16 | cxb1.6 | N-loop | SER 23 | A | HBDonor |
| Gln 16 | cxb1.6 | N-loop | SER 23 | A | VdWContact |
| Leu 20 | cxb1.11 | N-loop | MET 24 | A | Hydrophobic |
| Ile 41 | B2.3 | B2 | PRO 27 | A | Hydrophobic |
| Gln 49 | B3.1 | B3 | PRO 27 | A | Hydrophobic |
| Gln 49 | B3.1 | B3 | PRO 27 | A | VdWContact |
| Gln 49 | B3.1 | B3 | PHE 29 | A | Hydrophobic |
| Val 50 | B3.2 | B3 | MET 24 | A | Hydrophobic |
| Val 50 | B3.2 | B3 | LYS 25 | A | VdWContact |
| Cys 51 | B3.3 | B3 | LYS 25 | A | Hydrophobic |
| Cys 51 | B3.3 | B3 | LYS 25 | A | HBDonor |
| Cys 51 | B3.3 | B3 | LYS 25 | A | VdWContact |
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