CCL5_HUMAN

  • Alternate name(s): C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, SIS-delta, Small-inducible cytokine A5, T cell-specific protein P228, TCP228, T-cell-specific protein RANTES, RANTES(3-68), RANTES(4-68)
  • Organism: Homo sapiens
  • UniProt ID: P13501 open_in_new


Sequence

N-term   CX   N-loop   B1   30s-loop   B2   40s-loop   B3   50s-loop   Helix  
31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62   63 67   68 69 70 71 72 73 74 75 76 80 81 82   83 84 85 86 87 88 89   90 91 94 95 96 97 99 100   101 102 103 104 105   106 112 113 114   115 116 117 118   119 120 121 122   123 124 125 126 127 128 129 130 131 132 133 134 135  
M K V S A A A L A V I L I A T A L C A P A S A S P Y S S D T T P   C C   F A Y I A R P L P R A H   I K E Y F Y T   S G K C S N P A   V V F V T   R K N R   Q V C A   N P E K   K W V R E Y I N S L E M S  

Snake Plot

S G K C S N P A 30s-loop R K N R 40s-loop N P E K 50s-loopN-term M K V S A A A L A V I L I A T A L C A P A S A S P Y S S D T T P C C F A Y I A R P L P R A H N-term T Y F Y E K I V V F V T A C V Q K W V R E Y I N S L E M S
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List of structures

PDB Method Resolution State Publication date Reference
1B3A X-ray 1.6 dimer 1999-04-23 10.1016/S1074-5521(99)80019-2 open_in_new
1EQT X-ray 1.6 dimer 2000-04-19 -
1HRJ Solution nmr 0.0 dimer 1996-10-14 10.1021/BI00029A005 open_in_new
1RTN Solution nmr 0.0 dimer 1995-06-03 10.1021/BI00016A004 open_in_new
1RTO Solution nmr 0.0 dimer 1995-06-03 10.1021/BI00016A004 open_in_new
1U4L X-ray 2.0 dimer 2004-11-09 10.1016/J.STR.2004.08.014 open_in_new
1U4M X-ray 2.0 dimer 2004-11-09 10.1016/J.STR.2004.08.014 open_in_new
1U4P X-ray 1.7 dimer 2004-11-09 10.1016/J.STR.2004.08.014 open_in_new
1U4R X-ray 2.2 dimer 2004-11-09 10.1016/J.STR.2004.08.014 open_in_new
2L9H Solution nmr; solution scattering 0.0 dimer 2011-06-22 10.1016/J.STR.2011.06.001 open_in_new
2VXW X-ray 1.7 oligomer 2008-07-29 10.1002/PROT.22542 open_in_new
5CMD X-ray 3.09 oligomer 2016-04-13 10.1073/PNAS.1523981113 open_in_new
5COY X-ray 1.44 dimer 2016-04-13 10.1073/PNAS.1523981113 open_in_new
5DNF X-ray 2.55 oligomer 2016-04-13 10.1073/PNAS.1523981113 open_in_new
5L2U X-ray 2.28 oligomer 2017-08-09 -
5UIW X-ray 2.2 monomer 2017-06-28 10.1016/J.IMMUNI.2017.05.002 open_in_new
6AEZ X-ray 1.63 trimer 2019-08-07 10.1016/J.JMB.2019.12.049 open_in_new
6C6D X-ray 5.5 oligomer 2019-01-23 -
6FGP Solution nmr 0.0 monomer 2018-04-18 10.1111/FEBS.14460 open_in_new
6LOG X-ray 2.55 dimer 2020-03-18 10.3390/IJMS21051689 open_in_new
6STK X-ray 1.52 dimer 2020-09-02 10.1074/JBC.RA120.013891 open_in_new
7O7F Cryo-em 3.15 monomer 2021-06-30 10.1126/SCIADV.ABG8685 open_in_new

Targets (Guide to Pharmacology)

No targets found