Interactions for 1PFM — Binding Partner: CXCL4


Structure details

  • Chemokine Chain: D
  • Partner Chain: A,B,C
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Chemokine diagram

K A G P H C P T A Q 30s-loop K N G R 40s-loop D L Q A 50s-loopC-term M S A K E L R C Q C V K T T S Q V R P R H N-term I V E L S T I L I A T L L C I K P L Y K K I I K K L L E S
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Interactions for this Binding Partner

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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Leu 11 66 CX GLN 11 B Hydrophobic
Leu 11 66 CX ILE 42 B VdWContact
Thr 25 84 B1 GLY 48 A HBDonor
Thr 25 84 B1 GLY 48 A VdWContact
Ser 26 85 B1 ILE 30 C VdWContact
Leu 27 86 B1 VAL 29 C HBAcceptor
Leu 27 86 B1 VAL 29 C VdWContact
Glu 28 87 B1 GLU 28 C VdWContact
Glu 28 87 B1 LYS 50 B Anionic
Val 29 88 B1 LEU 27 C Hydrophobic
Val 29 88 B1 LEU 27 C HBAcceptor
Val 29 88 B1 LEU 27 C HBDonor
Val 29 88 B1 LEU 27 C VdWContact
Val 29 88 B1 LEU 67 C Hydrophobic
Val 29 88 B1 SER 26 C VdWContact
Ile 30 89 B1 SER 26 C VdWContact
Lys 31 90 30s-loop LEU 67 C Hydrophobic
Lys 31 90 30s-loop LEU 67 C VdWContact
Lys 31 90 30s-loop GLU 69 C Cationic
Lys 31 90 30s-loop SER 70 C HBDonor
Lys 31 90 30s-loop SER 70 C VdWContact
His 35 94 30s-loop ARG 49 B Hydrophobic
His 35 94 30s-loop ARG 49 B VdWContact
Lys 46 106 40s-loop GLY 48 A HBAcceptor
Lys 46 106 40s-loop GLY 48 A VdWContact
Gly 48 113 40s-loop THR 25 A HBAcceptor
Gly 48 113 40s-loop THR 25 A VdWContact
Gly 48 113 40s-loop GLY 48 A VdWContact
Gly 48 113 40s-loop LYS 46 A HBDonor
Gly 48 113 40s-loop LYS 46 A VdWContact
Lys 50 115 B3 GLN 11 B VdWContact
Tyr 60 125 Helix LEU 68 C Hydrophobic
Tyr 60 125 Helix LEU 68 C VdWContact
Tyr 60 125 Helix ILE 64 C Hydrophobic
Ile 64 129 Helix ILE 64 C Hydrophobic
Ile 64 129 Helix TYR 60 C Hydrophobic
Leu 67 132 Helix LEU 55 C Hydrophobic
Leu 67 132 Helix LYS 31 C Hydrophobic
Leu 67 132 Helix LYS 31 C VdWContact
Leu 67 132 Helix VAL 29 C Hydrophobic
Leu 68 133 Helix LEU 55 C Hydrophobic
Leu 68 133 Helix TYR 60 C Hydrophobic
Leu 68 133 Helix TYR 60 C VdWContact
Ser 70 135 Helix LYS 31 C VdWContact

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