Interactions for 1PFN — Binding Partner: CXCL4


Structure details

  • Chemokine Chain: A
  • Partner Chain: B,C,D
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Chemokine diagram

K A G P H C P T A Q 30s-loop K N G R 40s-loop D L Q A 50s-loopC-term M S A K E L R C Q C V K T T S Q V R P R H N-term I V E L S T I L I A T L L C I K P L Y K K I I K K L L E S
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Interactions for this Binding Partner

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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Leu 11 66 CX ARG 9 C HBAcceptor
Leu 11 66 CX ARG 9 C VdWContact
Leu 11 66 CX CYS 10 C HBDonor
Leu 11 66 CX CYS 10 C VdWContact
Leu 11 66 CX GLN 11 C Hydrophobic
Leu 11 66 CX GLN 11 C VdWContact
Cys 12 67 CX ARG 9 C Anionic
Thr 25 84 B1 GLY 48 D HBDonor
Thr 25 84 B1 GLY 48 D VdWContact
Thr 25 84 B1 ILE 30 B VdWContact
Ser 26 85 B1 VAL 29 B VdWContact
Ser 26 85 B1 ILE 30 B VdWContact
Val 29 88 B1 LEU 27 B Hydrophobic
Val 29 88 B1 LEU 27 B HBDonor
Val 29 88 B1 LEU 27 B VdWContact
Val 29 88 B1 SER 26 B VdWContact
Val 29 88 B1 LEU 67 B Hydrophobic
Val 29 88 B1 LEU 67 B VdWContact
Ile 30 89 B1 SER 26 B VdWContact
Lys 31 90 30s-loop SER 70 B VdWContact
Lys 31 90 30s-loop LEU 67 B Hydrophobic
Lys 31 90 30s-loop LEU 67 B VdWContact
Lys 46 106 40s-loop GLY 48 D HBAcceptor
Lys 46 106 40s-loop GLY 48 D VdWContact
Gly 48 113 40s-loop LYS 46 D HBDonor
Gly 48 113 40s-loop LYS 46 D VdWContact
Gly 48 113 40s-loop GLY 48 D VdWContact
Leu 55 120 50s-loop LEU 68 B Hydrophobic
Leu 55 120 50s-loop LEU 68 B VdWContact
Leu 55 120 50s-loop LEU 67 B Hydrophobic
Tyr 60 125 Helix LEU 68 B VdWContact
Ile 64 129 Helix ILE 64 B Hydrophobic
Ile 64 129 Helix LEU 55 B Hydrophobic
Leu 67 132 Helix LYS 31 B Hydrophobic
Leu 67 132 Helix LYS 31 B VdWContact
Leu 67 132 Helix VAL 29 B Hydrophobic
Leu 68 133 Helix TYR 60 B VdWContact
Leu 68 133 Helix LEU 55 B Hydrophobic
Ser 70 135 Helix LYS 31 B VdWContact

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