Interactions for 5CMD — Binding Partner: CCL5
Structure details
- PDB ID: 5CMD open_in_new
- Protein: CCL5_HUMAN
- Organism: Homo sapiens
- UniProt ID: P13501 open_in_new
- Method: X-ray
- Resolution: 3.09 Å
- Date: April 13, 2016
- Reference: 10.1073/PNAS.1523981113 open_in_new
- State: Oligomer
- Chemokine Chain: D
- Partner Chain: A,B,C,E,F
Chemokine diagram
Interactions for this Binding Partner
Download list as CSV
| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Ser 5 | NTc.Cm5 | N-term | VAL 49 | C | VdWContact |
| Ser 5 | NTc.Cm5 | N-term | SER 31 | E | VdWContact |
| Ser 5 | NTc.Cm5 | N-term | GLY 32 | E | VdWContact |
| Ser 5 | NTc.Cm5 | N-term | GLN 48 | C | VdWContact |
| Thr 7 | NTc.Cm3 | N-term | CYS 10 | C | VdWContact |
| Thr 7 | NTc.Cm3 | N-term | VAL 40 | C | Hydrophobic |
| Thr 7 | NTc.Cm3 | N-term | PRO 9 | C | Hydrophobic |
| Thr 7 | NTc.Cm3 | N-term | PRO 9 | C | VdWContact |
| Thr 8 | NTc.Cm2 | N-term | CYS 10 | C | HBAcceptor |
| Thr 8 | NTc.Cm2 | N-term | CYS 10 | C | HBDonor |
| Thr 8 | NTc.Cm2 | N-term | CYS 10 | C | VdWContact |
| Thr 8 | NTc.Cm2 | N-term | PHE 12 | C | Hydrophobic |
| Thr 8 | NTc.Cm2 | N-term | PHE 12 | C | VdWContact |
| Pro 9 | NTc.Cm1 | N-term | THR 7 | C | Hydrophobic |
| Cys 10 | CX.1 | CX | THR 8 | C | HBAcceptor |
| Cys 10 | CX.1 | CX | THR 8 | C | HBDonor |
| Cys 10 | CX.1 | CX | THR 8 | C | VdWContact |
| Cys 10 | CX.1 | CX | THR 7 | C | VdWContact |
| Phe 12 | cxb1.1 | N-loop | LYS 33 | B | HBAcceptor |
| Phe 12 | cxb1.1 | N-loop | LYS 33 | B | VdWContact |
| Phe 12 | cxb1.1 | N-loop | THR 8 | C | VdWContact |
| Phe 12 | cxb1.1 | N-loop | LYS 33 | C | Hydrophobic |
| Ala 13 | cxb1.2 | N-loop | LYS 33 | B | Hydrophobic |
| Leu 19 | cxb1.11 | N-loop | TYR 29 | B | Hydrophobic |
| Leu 19 | cxb1.11 | N-loop | TYR 29 | B | VdWContact |
| Ala 22 | cxb1.16 | N-loop | MET 67 | B | Hydrophobic |
| His 23 | B1.1 | B1 | MET 67 | B | Hydrophobic |
| His 23 | B1.1 | B1 | ASN 63 | B | Hydrophobic |
| His 23 | B1.1 | B1 | ASN 63 | B | HBDonor |
| His 23 | B1.1 | B1 | ASN 63 | B | VdWContact |
| His 23 | B1.1 | B1 | ILE 62 | B | Hydrophobic |
| His 23 | B1.1 | B1 | GLU 66 | B | Hydrophobic |
| His 23 | B1.1 | B1 | GLU 66 | B | VdWContact |
| Glu 26 | B1.4 | B1 | ARG 47 | F | Anionic |
| Glu 26 | B1.4 | B1 | ARG 47 | F | VdWContact |
| Tyr 27 | B1.5 | B1 | ARG 47 | F | Hydrophobic |
| Tyr 27 | B1.5 | B1 | ARG 47 | F | HBAcceptor |
| Tyr 27 | B1.5 | B1 | ARG 47 | F | VdWContact |
| Tyr 29 | B1.7 | B1 | VAL 49 | F | Hydrophobic |
| Lys 33 | b1b2.10 | 30s-loop | ALA 13 | F | Hydrophobic |
| Lys 33 | b1b2.10 | 30s-loop | PHE 12 | C | Hydrophobic |
| Val 40 | B2.3 | B2 | THR 7 | C | Hydrophobic |
| Thr 43 | B2.6 | B2 | GLU 66 | B | VdWContact |
| Lys 45 | b2b3.4 | 40s-loop | GLU 66 | B | Hydrophobic |
| Arg 47 | b2b3.12 | 40s-loop | GLU 26 | B | Cationic |
| Gln 48 | B3.1 | B3 | ASP 6 | C | HBAcceptor |
| Gln 48 | B3.1 | B3 | ASP 6 | C | VdWContact |
| Gln 48 | B3.1 | B3 | SER 5 | C | HBDonor |
| Gln 48 | B3.1 | B3 | SER 5 | C | VdWContact |
| Cys 50 | B3.3 | B3 | ASP 6 | C | Hydrophobic |
| Cys 50 | B3.3 | B3 | ASP 6 | C | HBDonor |
| Cys 50 | B3.3 | B3 | ASP 6 | C | VdWContact |
| Ile 62 | H.7 | Helix | HIS 23 | F | Hydrophobic |
| Asn 63 | H.8 | Helix | HIS 23 | F | Hydrophobic |
| Asn 63 | H.8 | Helix | HIS 23 | F | VdWContact |
| Leu 65 | H.10 | Helix | LYS 45 | F | Hydrophobic |
| Leu 65 | H.10 | Helix | LYS 45 | F | VdWContact |
| Glu 66 | CT.1 | C-term | HIS 23 | F | Hydrophobic |
| Glu 66 | CT.1 | C-term | HIS 23 | F | VdWContact |
| Glu 66 | CT.1 | C-term | LYS 45 | F | HBAcceptor |
| Glu 66 | CT.1 | C-term | LYS 45 | F | VdWContact |
| Glu 66 | CT.1 | C-term | THR 43 | F | HBAcceptor |
| Glu 66 | CT.1 | C-term | THR 43 | F | VdWContact |
| Met 67 | CT.2 | C-term | HIS 23 | F | Hydrophobic |
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