Interactions
6LFM | CXCL8_HUMAN — CXCL8
Residue contacts: 37
SUMMARY
- Protein
- CXCL8_HUMAN View protein entry
- Organism
- Homo sapiens
- UniProt ID
- P10145 View on UniProt
- PDB ID
- 6LFM View on PDB
- Method
- Cryo-em
- Resolution
- 3.5 Å
- Date
- Sept. 2, 2020
- Reference
- 10.1038/S41586-020-2492-5 Open DOI
- State
- Dimer
Chain information
- Chemokine chain
- D
- Partner chain
- E
3D VIEW
INTERACTION TABLE
Download CSV| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Lys 23 | B1.3 | B1 | GLU 29 | E | VdWContact |
| Lys 23 | B1.3 | B1 | GLY 31 | E | VdWContact |
| Lys 23 | B1.3 | B1 | SER 30 | E | HBDonor |
| Lys 23 | B1.3 | B1 | SER 30 | E | VdWContact |
| Glu 24 | B1.4 | B1 | VAL 27 | E | VdWContact |
| Glu 24 | B1.4 | B1 | ARG 26 | E | Anionic |
| Leu 25 | B1.5 | B1 | VAL 27 | E | Hydrophobic |
| Leu 25 | B1.5 | B1 | VAL 27 | E | HBAcceptor |
| Leu 25 | B1.5 | B1 | VAL 27 | E | HBDonor |
| Leu 25 | B1.5 | B1 | VAL 27 | E | VdWContact |
| Leu 25 | B1.5 | B1 | ARG 26 | E | VdWContact |
| Arg 26 | B1.6 | B1 | ARG 26 | E | Hydrophobic |
| Arg 26 | B1.6 | B1 | ARG 26 | E | VdWContact |
| Arg 26 | B1.6 | B1 | LEU 25 | E | VdWContact |
| Val 27 | B1.7 | B1 | PHE 65 | E | Hydrophobic |
| Val 27 | B1.7 | B1 | GLU 24 | E | VdWContact |
| Val 27 | B1.7 | B1 | LEU 25 | E | Hydrophobic |
| Val 27 | B1.7 | B1 | LEU 25 | E | HBAcceptor |
| Val 27 | B1.7 | B1 | LEU 25 | E | HBDonor |
| Val 27 | B1.7 | B1 | LEU 25 | E | VdWContact |
| Ile 28 | b1b2.4 | 30s-loop | GLU 24 | E | Hydrophobic |
| Glu 29 | b1b2.6 | 30s-loop | PHE 65 | E | Hydrophobic |
| Glu 29 | b1b2.6 | 30s-loop | LYS 23 | E | HBAcceptor |
| Glu 29 | b1b2.6 | 30s-loop | LYS 23 | E | HBDonor |
| Glu 29 | b1b2.6 | 30s-loop | LYS 23 | E | Anionic |
| Glu 29 | b1b2.6 | 30s-loop | LYS 23 | E | VdWContact |
| Thr 37 | b1b2.16 | 30s-loop | ALA 69 | E | Hydrophobic |
| Phe 65 | H.10 | Helix | GLU 29 | E | Hydrophobic |
| Phe 65 | H.10 | Helix | VAL 27 | E | Hydrophobic |
| Leu 66 | CT.1 | C-term | VAL 27 | E | Hydrophobic |
| Leu 66 | CT.1 | C-term | VAL 27 | E | VdWContact |
| Leu 66 | CT.1 | C-term | LEU 66 | E | Hydrophobic |
| Ala 69 | CT.4 | C-term | GLU 29 | E | Hydrophobic |
| Ala 69 | CT.4 | C-term | GLU 29 | E | VdWContact |
| Glu 70 | CT.5 | C-term | GLN 59 | E | VdWContact |
| Ser 72 | CT.7 | C-term | THR 37 | E | HBAcceptor |
| Ser 72 | CT.7 | C-term | THR 37 | E | VdWContact |
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