Interactions for 6LFM — Binding Partner: CXCL8
Structure details
- PDB ID: 6LFM open_in_new
- Protein: CXCL8_HUMAN
- Organism: Homo sapiens
- UniProt ID: P10145 open_in_new
- Method: Cryo-em
- Resolution: 3.5 Å
- Date: Sept. 2, 2020
- Reference: 10.1038/S41586-020-2492-5 open_in_new
- State: Dimer
- Chemokine Chain: D
- Partner Chain: E
Chemokine diagram
Interactions for this Binding Partner
Download list as CSV
Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
---|---|---|---|---|---|
Lys 23 | B1.3 | B1 | GLU 29 | E | VdWContact |
Lys 23 | B1.3 | B1 | GLY 31 | E | VdWContact |
Lys 23 | B1.3 | B1 | SER 30 | E | HBDonor |
Lys 23 | B1.3 | B1 | SER 30 | E | VdWContact |
Glu 24 | B1.4 | B1 | VAL 27 | E | VdWContact |
Glu 24 | B1.4 | B1 | ARG 26 | E | Anionic |
Leu 25 | B1.5 | B1 | VAL 27 | E | Hydrophobic |
Leu 25 | B1.5 | B1 | VAL 27 | E | HBAcceptor |
Leu 25 | B1.5 | B1 | VAL 27 | E | HBDonor |
Leu 25 | B1.5 | B1 | VAL 27 | E | VdWContact |
Leu 25 | B1.5 | B1 | ARG 26 | E | VdWContact |
Arg 26 | B1.6 | B1 | ARG 26 | E | Hydrophobic |
Arg 26 | B1.6 | B1 | ARG 26 | E | VdWContact |
Arg 26 | B1.6 | B1 | LEU 25 | E | VdWContact |
Val 27 | B1.7 | B1 | PHE 65 | E | Hydrophobic |
Val 27 | B1.7 | B1 | GLU 24 | E | VdWContact |
Val 27 | B1.7 | B1 | LEU 25 | E | Hydrophobic |
Val 27 | B1.7 | B1 | LEU 25 | E | HBAcceptor |
Val 27 | B1.7 | B1 | LEU 25 | E | HBDonor |
Val 27 | B1.7 | B1 | LEU 25 | E | VdWContact |
Ile 28 | b1b2.4 | 30s-loop | GLU 24 | E | Hydrophobic |
Glu 29 | b1b2.6 | 30s-loop | PHE 65 | E | Hydrophobic |
Glu 29 | b1b2.6 | 30s-loop | LYS 23 | E | HBAcceptor |
Glu 29 | b1b2.6 | 30s-loop | LYS 23 | E | HBDonor |
Glu 29 | b1b2.6 | 30s-loop | LYS 23 | E | Anionic |
Glu 29 | b1b2.6 | 30s-loop | LYS 23 | E | VdWContact |
Thr 37 | b1b2.16 | 30s-loop | ALA 69 | E | Hydrophobic |
Phe 65 | H.10 | Helix | GLU 29 | E | Hydrophobic |
Phe 65 | H.10 | Helix | VAL 27 | E | Hydrophobic |
Leu 66 | CT.1 | C-term | VAL 27 | E | Hydrophobic |
Leu 66 | CT.1 | C-term | VAL 27 | E | VdWContact |
Leu 66 | CT.1 | C-term | LEU 66 | E | Hydrophobic |
Ala 69 | CT.4 | C-term | GLU 29 | E | Hydrophobic |
Ala 69 | CT.4 | C-term | GLU 29 | E | VdWContact |
Glu 70 | CT.5 | C-term | GLN 59 | E | VdWContact |
Ser 72 | CT.7 | C-term | THR 37 | E | HBAcceptor |
Ser 72 | CT.7 | C-term | THR 37 | E | VdWContact |