Interactions

8XWN | CXCL8_HUMAN — CXCL8

Residue contacts: 47
SUMMARY
Protein
CXCL8_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
P10145 View on UniProt
PDB ID
8XWN View on PDB
Method
Cryo-em
Resolution
3.29 Å
Date
Jan. 15, 2025
Reference
-
State
Dimer
Chain information
Chemokine chain
E
Partner chain
D
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INTERACTION TABLE
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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Lys 30 B1.3 B1 GLU 36 D HBAcceptor
Lys 30 B1.3 B1 GLU 36 D Cationic
Lys 30 B1.3 B1 GLU 36 D VdWContact
Glu 31 B1.4 B1 ILE 35 D Hydrophobic
Glu 31 B1.4 B1 ILE 35 D VdWContact
Glu 31 B1.4 B1 VAL 34 D VdWContact
Glu 31 B1.4 B1 ARG 33 D Anionic
Leu 32 B1.5 B1 VAL 34 D HBAcceptor
Leu 32 B1.5 B1 VAL 34 D HBDonor
Leu 32 B1.5 B1 VAL 34 D VdWContact
Leu 32 B1.5 B1 ARG 33 D VdWContact
Arg 33 B1.6 B1 GLU 31 D HBDonor
Arg 33 B1.6 B1 GLU 31 D Cationic
Arg 33 B1.6 B1 GLU 31 D VdWContact
Arg 33 B1.6 B1 LEU 32 D VdWContact
Val 34 B1.7 B1 GLU 31 D VdWContact
Val 34 B1.7 B1 LEU 32 D HBAcceptor
Val 34 B1.7 B1 LEU 32 D HBDonor
Val 34 B1.7 B1 LEU 32 D VdWContact
Val 34 B1.7 B1 PHE 72 D Hydrophobic
Val 34 B1.7 B1 LEU 73 D Hydrophobic
Ile 35 b1b2.4 30s-loop GLU 31 D Hydrophobic
Ile 35 b1b2.4 30s-loop GLU 31 D VdWContact
Glu 36 b1b2.6 30s-loop ARG 75 D HBAcceptor
Glu 36 b1b2.6 30s-loop ARG 75 D Anionic
Glu 36 b1b2.6 30s-loop ARG 75 D VdWContact
Glu 36 b1b2.6 30s-loop ALA 76 D Hydrophobic
Glu 36 b1b2.6 30s-loop LYS 30 D HBDonor
Glu 36 b1b2.6 30s-loop LYS 30 D Anionic
Glu 36 b1b2.6 30s-loop LYS 30 D VdWContact
Glu 36 b1b2.6 30s-loop PHE 72 D Hydrophobic
Gln 66 H.4 Helix GLU 77 D VdWContact
Phe 72 H.10 Helix GLU 36 D Hydrophobic
Phe 72 H.10 Helix VAL 34 D Hydrophobic
Leu 73 CT.1 C-term VAL 34 D Hydrophobic
Leu 73 CT.1 C-term VAL 69 D Hydrophobic
Leu 73 CT.1 C-term LEU 73 D Hydrophobic
Leu 73 CT.1 C-term LEU 73 D VdWContact
Arg 75 CT.3 C-term GLU 36 D HBDonor
Arg 75 CT.3 C-term GLU 36 D Cationic
Arg 75 CT.3 C-term GLU 36 D VdWContact
Ala 76 CT.4 C-term THR 44 D Hydrophobic
Ala 76 CT.4 C-term THR 44 D HBAcceptor
Ala 76 CT.4 C-term THR 44 D VdWContact
Ala 76 CT.4 C-term VAL 34 D Hydrophobic
Glu 77 CT.5 C-term LYS 61 D HBAcceptor
Glu 77 CT.5 C-term LYS 61 D VdWContact
CHEMOKINE DIAGRAM
I E S G P H C A N T 30s-loop S D G R 40s-loop D P K E 50s-loopC-term V R L E K I F E I I V K L L C L E N W V Q R V V E K F L K R A E N
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical