Interactions for 7SK4 — Binding Partner: ACKR3


Structure details

  • Chemokine Chain: B
  • Partner Chain: A
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Chemokine diagram

L N T P N C A L 30s-loop K N N N R 40s-loop D P K L 50s-loopC-term L R H Q S L S Y R C P C R F F E S H V A R A N-term I K L H K V N Q I V A R L I C V Q K W I Q E Y L E K A L N K

Interactions for this Binding Partner

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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Gly - NTc.Cm9 N-term SER 216 A VdWContact
Gly - NTc.Cm9 N-term LEU 128 A Hydrophobic
Gly - NTc.Cm9 N-term PHE 129 A Hydrophobic
Gly - NTc.Cm9 N-term ILE 132 A Hydrophobic
Lys 1 NTc.Cm8 N-term ASP 179 A Cationic
Lys 1 NTc.Cm8 N-term ASP 179 A VdWContact
Lys 1 NTc.Cm8 N-term TYR 200 A VdWContact
Lys 1 NTc.Cm8 N-term GLU 213 A HBDonor
Lys 1 NTc.Cm8 N-term GLU 213 A Cationic
Lys 1 NTc.Cm8 N-term HIS 121 A Hydrophobic
Pro 2 NTc.Cm7 N-term GLN 301 A Hydrophobic
Pro 2 NTc.Cm7 N-term LEU 104 A Hydrophobic
Pro 2 NTc.Cm7 N-term TRP 100 A Hydrophobic
Pro 2 NTc.Cm7 N-term TRP 100 A VdWContact
Val 3 NTc.Cm6 N-term GLN 301 A VdWContact
Val 3 NTc.Cm6 N-term LEU 297 A Hydrophobic
Ser 4 NTc.Cm5 N-term SER 103 A HBAcceptor
Ser 4 NTc.Cm5 N-term SER 103 A VdWContact
Leu 5 NTc.Cm4 N-term TRP 100 A Hydrophobic
Leu 5 NTc.Cm4 N-term TRP 100 A VdWContact
Leu 5 NTc.Cm4 N-term LEU 183 A Hydrophobic
Leu 5 NTc.Cm4 N-term HIS 121 A Hydrophobic
Leu 5 NTc.Cm4 N-term HIS 121 A VdWContact
Leu 5 NTc.Cm4 N-term CYS 196 A Hydrophobic
Leu 5 NTc.Cm4 N-term CYS 196 A VdWContact
Tyr 7 NTc.Cm2 N-term ARG 197 A PiCation
Tyr 7 NTc.Cm2 N-term ARG 197 A VdWContact
Tyr 7 NTc.Cm2 N-term TYR 195 A Hydrophobic
Tyr 7 NTc.Cm2 N-term TYR 195 A PiStacking
Arg 8 NTc.Cm1 N-term GLU 290 A Cationic
Arg 8 NTc.Cm1 N-term ASP 275 A Cationic
Arg 8 NTc.Cm1 N-term ASP 275 A VdWContact
Pro 10 CX.4 CX PHE 285 A Hydrophobic
Arg 12 cxb1.1 N-loop LEU 209 A Hydrophobic
Arg 12 cxb1.1 N-loop ASP 275 A Cationic
Arg 12 cxb1.1 N-loop ILE 279 A VdWContact
Phe 13 cxb1.2 N-loop LYS 206 A Hydrophobic
Phe 13 cxb1.2 N-loop ILE 205 A Hydrophobic
Phe 13 cxb1.2 N-loop LEU 280 A Hydrophobic
Phe 13 cxb1.2 N-loop ILE 279 A Hydrophobic
Arg 20 cxb1.15 N-loop ILE 27 A Hydrophobic
Val 23 B1.2 B1 ILE 27 A Hydrophobic
Lys 24 B1.3 B1 VAL 28 A VdWContact
His 25 B1.4 B1 VAL 28 A Hydrophobic
Leu 26 B1.5 B1 VAL 29 A Hydrophobic
Leu 26 B1.5 B1 VAL 28 A HBDonor
Leu 26 B1.5 B1 VAL 28 A VdWContact
Leu 26 B1.5 B1 ILE 27 A Hydrophobic
Lys 27 B1.6 B1 VAL 32 A VdWContact
Lys 27 B1.6 B1 ASP 30 A Cationic
Lys 27 B1.6 B1 ASP 30 A VdWContact
Ile 28 B1.7 B1 VAL 32 A HBAcceptor
Ile 28 B1.7 B1 VAL 32 A VdWContact
Ile 28 B1.7 B1 ASP 30 A HBDonor
Ile 28 B1.7 B1 ASP 30 A VdWContact
Ile 28 B1.7 B1 THR 31 A Hydrophobic
Ile 28 B1.7 B1 THR 31 A VdWContact
Leu 29 b1b2.4 30s-loop VAL 32 A Hydrophobic
Leu 29 b1b2.4 30s-loop VAL 32 A VdWContact
Asn 30 b1b2.7 30s-loop VAL 32 A HBDonor
Asn 30 b1b2.7 30s-loop VAL 32 A VdWContact
Asn 30 b1b2.7 30s-loop CYS 34 A HBAcceptor
Asn 30 b1b2.7 30s-loop CYS 34 A VdWContact
Thr 31 b1b2.8 30s-loop CYS 34 A Hydrophobic
Thr 31 b1b2.8 30s-loop CYS 34 A VdWContact
Val 39 B2.3 B2 HIS 281 A Hydrophobic
Arg 47 b2b3.12 40s-loop LEU 280 A HBDonor
Arg 47 b2b3.12 40s-loop LEU 280 A VdWContact
Arg 47 b2b3.12 40s-loop TYR 282 A VdWContact
Gln 48 B3.1 B3 HIS 281 A Hydrophobic
Gln 48 B3.1 B3 HIS 281 A VdWContact
Cys 50 B3.3 B3 HIS 281 A Hydrophobic
Tyr 61 H.6 Helix VAL 29 A Hydrophobic
Tyr 61 H.6 Helix VAL 29 A VdWContact
Ala 65 H.10 Helix VAL 29 A Hydrophobic
Leu 66 CT.1 C-term THR 31 A Hydrophobic

Interaction pattern search
(0.00 = no similarity, 1.00 = identical)