CXCL5_HUMAN

  • Alternate name(s): C-X-C motif chemokine 5
  • Organism: Homo sapiens
  • UniProt ID: P42830 open_in_new


Wild type sequence

Residue N-term   CX   N-loop   B1   30s-loop   B2   40s-loop   B3   50s-loop   Helix   C-term  
  NTc.Cm48 NTc.Cm47 NTc.Cm46 NTc.Cm45 NTc.Cm44 NTc.Cm43 NTc.Cm42 NTc.Cm41 NTc.Cm40 NTc.Cm39 NTc.Cm38 NTc.Cm37 NTc.Cm36 NTc.Cm35 NTc.Cm34 NTc.Cm33 NTc.Cm32 NTc.Cm31 NTc.Cm30 NTc.Cm29 NTc.Cm28 NTc.Cm27 NTc.Cm26 NTc.Cm25 NTc.Cm24 NTc.Cm23 NTc.Cm22 NTc.Cm21 NTc.Cm20 NTc.Cm19 NTc.Cm18 NTc.Cm17 NTc.Cm16 NTc.Cm15 NTc.Cm14 NTc.Cm13 NTc.Cm12 NTc.Cm11 NTc.Cm10 NTc.Cm9 NTc.Cm8 NTc.Cm7 NTc.Cm6 NTc.Cm5 NTc.Cm4 NTc.Cm3 NTc.Cm2 NTc.Cm1   CX.1 CX.4 CX.5   cxb1.1 cxb1.2 cxb1.5 cxb1.6 cxb1.8 cxb1.10 cxb1.11 cxb1.14 cxb1.15 cxb1.16   B1.1 B1.2 B1.3 B1.4 B1.5 B1.6 B1.7   b1b2.4 b1b2.6 b1b2.7 b1b2.8 b1b2.9 b1b2.10 b1b2.12 b1b2.13 b1b2.14 b1b2.16   B2.1 B2.2 B2.3 B2.4 B2.5 B2.6   b2b3.2 b2b3.4 b2b3.11 b2b3.12   B3.1 B3.2 B3.3 B3.4   b3h.1 b3h.2 b3h.3 b3h.4   H.1 H.2 H.3 H.4 H.5 H.6 H.7 H.8 H.9 H.10   CT.1 CT.2 CT.3 CT.4 CT.5 CT.6 CT.7 CT.8  
Wild Type M S L L S S R A A R V P G P S S S L C A L L V L L L L L T Q P G P I A S A G P A A A V L R E L R   C V C   L Q T T Q G V H P K   M I S N L Q V   F A I G P Q C S K V   E V V A S L   K N G K   E I C L   D P E A   P F L K K V I Q K I   L D G G N K E N  

Snake Plot

F A I G P Q C S K V 30s-loop K N G K 40s-loop D P E A 50s-loopC-term M S L L S S R A A R V P G P S S S L C A L L V L L L L L T Q P G P I A S A G P A A A V L R E L R C V C L Q T T Q G V H P K N-term V Q L N S I M E V V A S L L C I E P F L K K V I Q K I L D G G N K E N
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List of structures

PDB Method Resolution State Publication date Reference
2MGS - A,B Nmr None Dimer 2014-04-02 10.1371/JOURNAL.PONE.0093228 open_in_new
8XWS - D,B Cryo-em 3.06 Dimer 2025-01-15 -
8XX7 - D,B Cryo-em 3.32 Dimer 2025-01-15 -

Sequence alignment from structures

Position NTc.Cm48 NTc.Cm47 NTc.Cm46 NTc.Cm45 NTc.Cm44 NTc.Cm43 NTc.Cm42 NTc.Cm41 NTc.Cm40 NTc.Cm39 NTc.Cm38 NTc.Cm37 NTc.Cm36 NTc.Cm35 NTc.Cm34 NTc.Cm33 NTc.Cm32 NTc.Cm31 NTc.Cm30 NTc.Cm29 NTc.Cm28 NTc.Cm27 NTc.Cm26 NTc.Cm25 NTc.Cm24 NTc.Cm23 NTc.Cm22 NTc.Cm21 NTc.Cm20 NTc.Cm19 NTc.Cm18 NTc.Cm17 NTc.Cm16 NTc.Cm15 NTc.Cm14 NTc.Cm13 NTc.Cm12 NTc.Cm11 NTc.Cm10 NTc.Cm9 NTc.Cm8 NTc.Cm7 NTc.Cm6 NTc.Cm5 NTc.Cm4 NTc.Cm3 NTc.Cm2 NTc.Cm1 CX.1 CX.4 CX.5 cxb1.1 cxb1.2 cxb1.5 cxb1.6 cxb1.8 cxb1.10 cxb1.11 cxb1.14 cxb1.15 cxb1.16 B1.1 B1.2 B1.3 B1.4 B1.5 B1.6 B1.7 b1b2.4 b1b2.6 b1b2.7 b1b2.8 b1b2.9 b1b2.10 b1b2.12 b1b2.13 b1b2.14 b1b2.16 B2.1 B2.2 B2.3 B2.4 B2.5 B2.6 b2b3.2 b2b3.4 b2b3.11 b2b3.12 B3.1 B3.2 B3.3 B3.4 b3h.1 b3h.2 b3h.3 b3h.4 H.1 H.2 H.3 H.4 H.5 H.6 H.7 H.8 H.9 H.10 CT.1 CT.2 CT.3 CT.4 CT.5 CT.6 CT.7 CT.8
Canonical Sequence M S L L S S R A A R V P G P S S S L C A L L V L L L L L T Q P G P I A S A G P A A A V L R E L R C V C L Q T T Q G V H P K M I S N L Q V F A I G P Q C S K V E V V A S L K N G K E I C L D P E A P F L K K V I Q K I L D G G N K E N
2MGS - A,B - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - L R E L R C V C L Q T T Q G V H P K M I S N L Q V F A I G P Q C S K V E V V A S L K N G K E I C L D P E A P F L K K V I Q K I L D G G N K E N
8XWS - D,B - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E L R C V C L Q T T Q G V H P K M I S N L Q V F A I G P Q C S K V E V V A S L K N G K E I C L D P E A P F L K K V I Q K I L D G G - - - -
8XX7 - D,B - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - E L R C V C L Q T T Q G V H P K M I S N L Q V F A I G P Q C S K V E V V A S L K N G K E I C L D P E A P F L K K V I Q K I L D G G - - - -