Interactions

8XX6 | CXCL8_HUMAN — CXCL8

Residue contacts: 47
SUMMARY
Protein
CXCL8_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
P10145 View on UniProt
PDB ID
8XX6 View on PDB
Method
Cryo-em
Resolution
2.99 Å
Date
Jan. 15, 2025
Reference
-
State
Dimer
Chain information
Chemokine chain
E
Partner chain
D
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INTERACTION TABLE
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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Lys 21 B1.3 B1 GLU 29 D HBAcceptor
Lys 21 B1.3 B1 GLU 29 D Cationic
Lys 21 B1.3 B1 GLU 29 D VdWContact
Glu 22 B1.4 B1 ARG 26 D Anionic
Glu 22 B1.4 B1 ILE 28 D Hydrophobic
Glu 22 B1.4 B1 ILE 28 D VdWContact
Glu 22 B1.4 B1 VAL 27 D VdWContact
Leu 23 B1.5 B1 ARG 26 D VdWContact
Leu 23 B1.5 B1 VAL 27 D HBAcceptor
Leu 23 B1.5 B1 VAL 27 D HBDonor
Leu 23 B1.5 B1 VAL 27 D VdWContact
Arg 24 B1.6 B1 GLU 24 D HBDonor
Arg 24 B1.6 B1 GLU 24 D Cationic
Arg 24 B1.6 B1 GLU 24 D VdWContact
Arg 24 B1.6 B1 LEU 25 D VdWContact
Val 25 B1.7 B1 LEU 66 D Hydrophobic
Val 25 B1.7 B1 PHE 65 D Hydrophobic
Val 25 B1.7 B1 GLU 24 D VdWContact
Val 25 B1.7 B1 LEU 25 D HBAcceptor
Val 25 B1.7 B1 LEU 25 D HBDonor
Val 25 B1.7 B1 LEU 25 D VdWContact
Ile 26 b1b2.4 30s-loop GLU 24 D Hydrophobic
Ile 26 b1b2.4 30s-loop GLU 24 D VdWContact
Glu 27 b1b2.6 30s-loop LYS 23 D HBDonor
Glu 27 b1b2.6 30s-loop LYS 23 D Anionic
Glu 27 b1b2.6 30s-loop LYS 23 D VdWContact
Glu 27 b1b2.6 30s-loop ALA 69 D Hydrophobic
Glu 27 b1b2.6 30s-loop PHE 65 D Hydrophobic
Glu 27 b1b2.6 30s-loop ARG 68 D HBAcceptor
Glu 27 b1b2.6 30s-loop ARG 68 D Anionic
Glu 27 b1b2.6 30s-loop ARG 68 D VdWContact
Gln 57 H.4 Helix GLU 70 D VdWContact
Phe 63 H.10 Helix GLU 29 D Hydrophobic
Phe 63 H.10 Helix VAL 27 D Hydrophobic
Leu 64 CT.1 C-term LEU 66 D Hydrophobic
Leu 64 CT.1 C-term LEU 66 D VdWContact
Leu 64 CT.1 C-term VAL 62 D Hydrophobic
Leu 64 CT.1 C-term VAL 27 D Hydrophobic
Arg 66 CT.3 C-term GLU 29 D HBDonor
Arg 66 CT.3 C-term GLU 29 D Cationic
Arg 66 CT.3 C-term GLU 29 D VdWContact
Ala 67 CT.4 C-term THR 37 D Hydrophobic
Ala 67 CT.4 C-term THR 37 D HBAcceptor
Ala 67 CT.4 C-term THR 37 D VdWContact
Ala 67 CT.4 C-term VAL 27 D Hydrophobic
Glu 68 CT.5 C-term LYS 54 D HBAcceptor
Glu 68 CT.5 C-term LYS 54 D VdWContact
CHEMOKINE DIAGRAM
I E S G P H C A N T 30s-loop S D G R 40s-loop D P K E 50s-loopC-term V R L E K I F E I I V K L L C L E N W V Q R V V E K F L K R A E N
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical