Interactions for 7XA3 — Binding Partner: CCR1
Structure details
- PDB ID: 7XA3 open_in_new
- Protein: CCL2_HUMAN
- Organism: Homo sapiens
- UniProt ID: P13500 open_in_new
- Method: Cryo-em
- Resolution: 2.9 Å
- Date: Aug. 24, 2022
- Reference: 10.1038/S41421-022-00403-4 open_in_new
- State: Monomer
- Chemokine Chain: L
- Partner Chain: R
Chemokine diagram
Interactions for this Binding Partner
Download list as CSV
| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Gln 1 | NTc.Cm10 | N-term | TRP 98 | R | Hydrophobic |
| Gln 1 | NTc.Cm10 | N-term | TRP 98 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | GLY 191 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | PRO 192 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | THR 117 | R | Hydrophobic |
| Gln 1 | NTc.Cm10 | N-term | THR 117 | R | HBDonor |
| Gln 1 | NTc.Cm10 | N-term | THR 117 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | TYR 120 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | HIS 121 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | CYS 190 | R | VdWContact |
| Pro 2 | NTc.Cm9 | N-term | GLU 291 | R | Hydrophobic |
| Pro 2 | NTc.Cm9 | N-term | TRP 98 | R | Hydrophobic |
| Pro 2 | NTc.Cm9 | N-term | TYR 120 | R | Hydrophobic |
| Asp 3 | NTc.Cm8 | N-term | THR 287 | R | Hydrophobic |
| Asp 3 | NTc.Cm8 | N-term | THR 287 | R | VdWContact |
| Ala 4 | NTc.Cm7 | N-term | GLN 288 | R | Hydrophobic |
| Ala 4 | NTc.Cm7 | N-term | LEU 45 | R | Hydrophobic |
| Ile 5 | NTc.Cm6 | N-term | TRP 98 | R | Hydrophobic |
| Asn 6 | NTc.Cm5 | N-term | GLY 191 | R | VdWContact |
| Asn 6 | NTc.Cm5 | N-term | CYS 190 | R | HBDonor |
| Asn 6 | NTc.Cm5 | N-term | CYS 190 | R | VdWContact |
| Ala 7 | NTc.Cm4 | N-term | HIS 33 | R | Hydrophobic |
| Pro 8 | NTc.Cm3 | N-term | HIS 33 | R | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | GLN 269 | R | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | SER 275 | R | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | CYS 32 | R | Hydrophobic |
| Tyr 13 | cxb1.1 | N-loop | CYS 32 | R | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | THR 280 | R | Hydrophobic |
| Tyr 13 | cxb1.1 | N-loop | THR 280 | R | VdWContact |
| Arg 29 | B1.6 | B1 | ASP 185 | R | Cationic |
| Arg 29 | B1.6 | B1 | ASP 185 | R | VdWContact |
| Ser 34 | b1b2.9 | 30s-loop | PHE 194 | R | HBDonor |
| Ser 34 | b1b2.9 | 30s-loop | PHE 194 | R | VdWContact |
| Ser 34 | b1b2.9 | 30s-loop | ASN 199 | R | VdWContact |
| Cys 36 | b1b2.12 | 30s-loop | ARG 196 | R | HBAcceptor |
| Cys 36 | b1b2.12 | 30s-loop | ARG 196 | R | VdWContact |
| Pro 37 | b1b2.13 | 30s-loop | ARG 196 | R | VdWContact |
| Glu 50 | B3.1 | B3 | PRO 31 | R | Hydrophobic |
| Glu 50 | B3.1 | B3 | PRO 31 | R | VdWContact |
| Glu 50 | B3.1 | B3 | ALA 30 | R | HBAcceptor |
| Glu 50 | B3.1 | B3 | ALA 30 | R | VdWContact |
| Cys 52 | B3.3 | B3 | ALA 30 | R | Hydrophobic |
| Cys 52 | B3.3 | B3 | ALA 30 | R | VdWContact |
, 'snake_.png', {scale: 3});){kind=link}
, 'snake_.jpg', {scale: 3});){kind=link}