Interactions

8XX7 | CXCL5_HUMAN — CXCR2

Residue contacts: 41
SUMMARY
Protein
CXCL5_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
P42830 View on UniProt
PDB ID
8XX7 View on PDB
Method
Cryo-em
Resolution
3.32 Å
Date
Jan. 15, 2025
Reference
-
State
Dimer
Chain information
Chemokine chain
B
Partner chain
C
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INTERACTION TABLE
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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Glu 10 NTc.Cm3 N-term ARG 208 C HBAcceptor
Glu 10 NTc.Cm3 N-term ARG 208 C Anionic
Glu 10 NTc.Cm3 N-term ARG 208 C VdWContact
Glu 10 NTc.Cm3 N-term ARG 278 C Anionic
Glu 10 NTc.Cm3 N-term ARG 278 C VdWContact
Glu 10 NTc.Cm3 N-term LEU 296 C Hydrophobic
Glu 10 NTc.Cm3 N-term LEU 296 C VdWContact
Glu 10 NTc.Cm3 N-term ARG 212 C HBAcceptor
Glu 10 NTc.Cm3 N-term ARG 212 C Anionic
Glu 10 NTc.Cm3 N-term ARG 212 C VdWContact
Leu 11 NTc.Cm2 N-term ARG 278 C HBAcceptor
Leu 11 NTc.Cm2 N-term ARG 278 C VdWContact
Leu 11 NTc.Cm2 N-term TYR 197 C Hydrophobic
Leu 11 NTc.Cm2 N-term VAL 187 C Hydrophobic
Arg 12 NTc.Cm1 N-term ASP 293 C HBDonor
Arg 12 NTc.Cm1 N-term ASP 293 C Cationic
Arg 12 NTc.Cm1 N-term ASP 293 C VdWContact
Arg 12 NTc.Cm1 N-term ASP 274 C HBDonor
Arg 12 NTc.Cm1 N-term ASP 274 C Cationic
Arg 12 NTc.Cm1 N-term ASP 274 C VdWContact
Cys 13 CX.1 CX ARG 289 C HBAcceptor
Cys 13 CX.1 CX ARG 289 C VdWContact
Val 14 CX.4 CX PRO 38 C Hydrophobic
Val 14 CX.4 CX PRO 38 C VdWContact
Leu 16 cxb1.1 N-loop CYS 39 C Hydrophobic
Leu 16 cxb1.1 N-loop GLU 284 C Hydrophobic
Leu 16 cxb1.1 N-loop ARG 289 C VdWContact
Thr 19 cxb1.6 N-loop ALA 36 C VdWContact
Thr 19 cxb1.6 N-loop LEU 33 C Hydrophobic
Ile 35 b1b2.7 30s-loop ASN 202 C Hydrophobic
Ile 35 b1b2.7 30s-loop ASN 202 C VdWContact
Pro 37 b1b2.9 30s-loop ASP 199 C Hydrophobic
Pro 37 b1b2.9 30s-loop TYR 197 C Hydrophobic
Pro 37 b1b2.9 30s-loop THR 204 C Hydrophobic
Pro 37 b1b2.9 30s-loop VAL 187 C Hydrophobic
Gln 38 b1b2.10 30s-loop SER 189 C HBDonor
Gln 38 b1b2.10 30s-loop SER 189 C VdWContact
Val 45 B2.3 B2 PRO 38 C Hydrophobic
Glu 53 B3.1 B3 PRO 38 C Hydrophobic
Ile 54 B3.2 B3 LEU 33 C Hydrophobic
Cys 55 B3.3 B3 PRO 38 C VdWContact
CHEMOKINE DIAGRAM
F A I G P Q C S K V 30s-loop K N G K 40s-loop D P E A 50s-loopC-term E L R C V C L Q T T Q G V H P K N-term V Q L N S I M E V V A S L L C I E P F L K K V I Q K I L D G G
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical