Interactions

1QE6 | CXCL8_HUMAN — CXCL8

Residue contacts: 66
SUMMARY
Protein
CXCL8_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
P10145 View on UniProt
PDB ID
1QE6 View on PDB
Method
X-ray
Resolution
2.35 Å
Date
March 22, 2000
Reference
2-S Open DOI
State
Dimer
Chain information
Chemokine chain
B
Partner chain
A
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INTERACTION TABLE
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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Lys 23 B1.3 B1 GLU 29 A HBAcceptor
Lys 23 B1.3 B1 GLU 29 A VdWContact
Glu 24 B1.4 B1 ILE 28 A Hydrophobic
Glu 24 B1.4 B1 ILE 28 A VdWContact
Glu 24 B1.4 B1 VAL 27 A VdWContact
Glu 24 B1.4 B1 ARG 26 A HBAcceptor
Glu 24 B1.4 B1 ARG 26 A Anionic
Glu 24 B1.4 B1 ARG 26 A VdWContact
Leu 25 B1.5 B1 VAL 27 A Hydrophobic
Leu 25 B1.5 B1 VAL 27 A HBAcceptor
Leu 25 B1.5 B1 VAL 27 A HBDonor
Leu 25 B1.5 B1 VAL 27 A VdWContact
Leu 25 B1.5 B1 ARG 26 A VdWContact
Arg 26 B1.6 B1 GLU 24 A HBDonor
Arg 26 B1.6 B1 GLU 24 A Cationic
Arg 26 B1.6 B1 GLU 24 A VdWContact
Arg 26 B1.6 B1 ARG 26 A Hydrophobic
Arg 26 B1.6 B1 LEU 25 A VdWContact
Val 27 B1.7 B1 LEU 66 A Hydrophobic
Val 27 B1.7 B1 LEU 66 A VdWContact
Val 27 B1.7 B1 ALA 69 A Hydrophobic
Val 27 B1.7 B1 GLU 24 A VdWContact
Val 27 B1.7 B1 PHE 65 A Hydrophobic
Val 27 B1.7 B1 LEU 25 A Hydrophobic
Val 27 B1.7 B1 LEU 25 A HBAcceptor
Val 27 B1.7 B1 LEU 25 A HBDonor
Val 27 B1.7 B1 LEU 25 A VdWContact
Ile 28 b1b2.4 30s-loop GLU 24 A Hydrophobic
Ile 28 b1b2.4 30s-loop GLU 24 A VdWContact
Glu 29 b1b2.6 30s-loop ALA 69 A Hydrophobic
Glu 29 b1b2.6 30s-loop ALA 69 A VdWContact
Glu 29 b1b2.6 30s-loop LYS 23 A HBDonor
Glu 29 b1b2.6 30s-loop LYS 23 A VdWContact
Glu 29 b1b2.6 30s-loop ARG 68 A HBAcceptor
Glu 29 b1b2.6 30s-loop ARG 68 A Anionic
Glu 29 b1b2.6 30s-loop ARG 68 A VdWContact
Glu 29 b1b2.6 30s-loop PHE 65 A Hydrophobic
Ser 30 b1b2.7 30s-loop SER 72 A VdWContact
Thr 37 b1b2.16 30s-loop ALA 69 A Hydrophobic
Thr 37 b1b2.16 30s-loop ALA 69 A HBDonor
Thr 37 b1b2.16 30s-loop ALA 69 A VdWContact
Thr 37 b1b2.16 30s-loop SER 72 A HBDonor
Thr 37 b1b2.16 30s-loop SER 72 A VdWContact
Pro 53 b3h.2 50s-loop GLU 70 A Hydrophobic
Lys 54 b3h.3 50s-loop SER 72 A Cationic
Lys 54 b3h.3 50s-loop SER 72 A VdWContact
Gln 59 H.4 Helix GLU 70 A Hydrophobic
Gln 59 H.4 Helix GLU 70 A VdWContact
Val 62 H.7 Helix LEU 66 A Hydrophobic
Glu 63 H.8 Helix GLU 63 A VdWContact
Phe 65 H.10 Helix GLU 29 A Hydrophobic
Phe 65 H.10 Helix VAL 27 A Hydrophobic
Leu 66 CT.1 C-term LEU 66 A Hydrophobic
Leu 66 CT.1 C-term VAL 62 A Hydrophobic
Leu 66 CT.1 C-term VAL 62 A VdWContact
Leu 66 CT.1 C-term VAL 27 A Hydrophobic
Arg 68 CT.3 C-term GLU 29 A HBDonor
Arg 68 CT.3 C-term GLU 29 A Cationic
Arg 68 CT.3 C-term GLU 29 A VdWContact
Ala 69 CT.4 C-term THR 37 A Hydrophobic
Ala 69 CT.4 C-term THR 37 A HBAcceptor
Ala 69 CT.4 C-term THR 37 A VdWContact
Ala 69 CT.4 C-term GLU 29 A Hydrophobic
Ala 69 CT.4 C-term VAL 27 A Hydrophobic
Ser 72 CT.7 C-term THR 37 A VdWContact
Ser 72 CT.7 C-term SER 30 A VdWContact
CHEMOKINE DIAGRAM
I E S G P C C A N T 30s-loop S D G R 40s-loop D P K E 50s-loopC-term A K E C R C Q C I K T Y S K P F H P K N-term V R L E K I F E I I V K L L C L E N W V Q R V V E K F L K R A E N S
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical