Interactions for 2IL8 — Binding Partner: CXCL8


Structure details

  • Chemokine Chain: A
  • Partner Chain: B
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Chemokine diagram

E S G P H C A N T E 30s-loop S D G R 40s-loop D P K E 50s-loopC-term A K E L R C Q C I K T Y S K P F H P K F N-term I V R L E K I I I V K L L C L E N W V Q R V V E K F L K R A E N S
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Interactions for this Binding Partner

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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Lys 23 84 B1 GLU 29 B HBAcceptor
Lys 23 84 B1 GLU 29 B VdWContact
Glu 24 85 B1 VAL 27 B VdWContact
Glu 24 85 B1 ARG 26 B Anionic
Glu 24 85 B1 ILE 28 B Hydrophobic
Leu 25 86 B1 VAL 27 B Hydrophobic
Leu 25 86 B1 VAL 27 B HBAcceptor
Leu 25 86 B1 VAL 27 B HBDonor
Leu 25 86 B1 VAL 27 B VdWContact
Arg 26 87 B1 ARG 26 B Hydrophobic
Arg 26 87 B1 GLU 24 B Cationic
Val 27 88 B1 LEU 25 B Hydrophobic
Val 27 88 B1 LEU 25 B HBAcceptor
Val 27 88 B1 LEU 25 B HBDonor
Val 27 88 B1 LEU 25 B VdWContact
Val 27 88 B1 PHE 65 B Hydrophobic
Val 27 88 B1 GLU 24 B VdWContact
Ile 28 89 B1 GLU 24 B Hydrophobic
Glu 29 90 30s-loop LYS 23 B HBDonor
Glu 29 90 30s-loop LYS 23 B VdWContact
Glu 29 90 30s-loop ARG 68 B VdWContact
Glu 29 90 30s-loop ALA 69 B Hydrophobic
Glu 29 90 30s-loop ALA 69 B VdWContact
Glu 29 90 30s-loop PHE 65 B Hydrophobic
Thr 37 99 30s-loop ALA 69 B Hydrophobic
Thr 37 99 30s-loop ALA 69 B HBDonor
Thr 37 99 30s-loop ALA 69 B VdWContact
Phe 65 132 Helix GLU 29 B Hydrophobic
Phe 65 132 Helix VAL 27 B Hydrophobic
Arg 68 135 Helix GLU 29 B VdWContact
Ala 69 136 C-term GLU 29 B Hydrophobic
Ala 69 136 C-term GLU 29 B VdWContact
Ala 69 136 C-term THR 37 B Hydrophobic
Ala 69 136 C-term THR 37 B HBAcceptor
Ala 69 136 C-term THR 37 B VdWContact

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