Interactions for 1PFM — Binding Partner: CXCL4
Structure details
- PDB ID: 1PFM open_in_new
- Protein: CXCL4_HUMAN
- Organism: Homo sapiens
- UniProt ID: P02776 open_in_new
- Method: Nmr
- Resolution:
- Date: Jan. 29, 1996
- Reference: 10.1021/BI00036A012 open_in_new
- State: Tetramer
- Chemokine Chain: A
- Partner Chain: B,C,D
Chemokine diagram
Interactions for this Binding Partner
Download list as CSV
| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Gln 9 | NTc.Cm1 | N-term | GLN 11 | C | HBDonor |
| Gln 9 | NTc.Cm1 | N-term | GLN 11 | C | VdWContact |
| Gln 9 | NTc.Cm1 | N-term | CYS 12 | C | VdWContact |
| Leu 11 | CX.4 | CX | GLN 11 | C | Hydrophobic |
| Leu 11 | CX.4 | CX | GLN 11 | C | VdWContact |
| Leu 11 | CX.4 | CX | LYS 50 | C | VdWContact |
| Cys 12 | CX.5 | CX | ARG 9 | C | Anionic |
| Val 13 | cxb1.1 | N-loop | ARG 9 | C | VdWContact |
| Thr 16 | cxb1.6 | N-loop | ARG 9 | C | HBAcceptor |
| Thr 16 | cxb1.6 | N-loop | ARG 9 | C | VdWContact |
| Gln 18 | cxb1.10 | N-loop | GLU 7 | C | Hydrophobic |
| Gln 18 | cxb1.10 | N-loop | GLU 7 | C | HBDonor |
| Gln 18 | cxb1.10 | N-loop | GLU 7 | C | VdWContact |
| Thr 25 | B1.3 | B1 | GLY 48 | D | HBDonor |
| Thr 25 | B1.3 | B1 | GLY 48 | D | VdWContact |
| Ser 26 | B1.4 | B1 | ILE 30 | B | VdWContact |
| Leu 27 | B1.5 | B1 | VAL 29 | B | HBAcceptor |
| Leu 27 | B1.5 | B1 | VAL 29 | B | VdWContact |
| Val 29 | B1.7 | B1 | LEU 67 | B | Hydrophobic |
| Val 29 | B1.7 | B1 | LEU 67 | B | VdWContact |
| Val 29 | B1.7 | B1 | VAL 29 | B | Hydrophobic |
| Val 29 | B1.7 | B1 | SER 26 | B | VdWContact |
| Val 29 | B1.7 | B1 | LEU 27 | B | HBAcceptor |
| Val 29 | B1.7 | B1 | LEU 27 | B | HBDonor |
| Val 29 | B1.7 | B1 | LEU 27 | B | VdWContact |
| Ile 30 | b1b2.4 | 30s-loop | SER 26 | B | VdWContact |
| Lys 31 | b1b2.6 | 30s-loop | LYS 66 | B | VdWContact |
| Lys 31 | b1b2.6 | 30s-loop | LEU 67 | B | Hydrophobic |
| Lys 31 | b1b2.6 | 30s-loop | LEU 67 | B | VdWContact |
| Lys 31 | b1b2.6 | 30s-loop | SER 70 | B | VdWContact |
| Lys 46 | b2b3.2 | 40s-loop | GLY 48 | D | HBAcceptor |
| Lys 46 | b2b3.2 | 40s-loop | GLY 48 | D | VdWContact |
| Gly 48 | b2b3.11 | 40s-loop | LYS 46 | D | HBDonor |
| Gly 48 | b2b3.11 | 40s-loop | LYS 46 | D | VdWContact |
| Gly 48 | b2b3.11 | 40s-loop | GLY 48 | D | VdWContact |
| Gly 48 | b2b3.11 | 40s-loop | THR 25 | D | HBAcceptor |
| Gly 48 | b2b3.11 | 40s-loop | THR 25 | D | VdWContact |
| Arg 49 | b2b3.12 | 40s-loop | PRO 34 | C | VdWContact |
| Lys 50 | B3.1 | B3 | GLU 28 | C | Cationic |
| Leu 55 | b3h.2 | 50s-loop | LEU 67 | B | Hydrophobic |
| Tyr 60 | H.3 | Helix | LEU 68 | B | VdWContact |
| Ile 64 | H.7 | Helix | ILE 64 | B | Hydrophobic |
| Leu 67 | H.10 | Helix | LYS 31 | B | Hydrophobic |
| Leu 67 | H.10 | Helix | LYS 31 | B | VdWContact |
| Leu 67 | H.10 | Helix | VAL 29 | B | Hydrophobic |
| Leu 68 | CT.1 | C-term | TYR 60 | B | VdWContact |
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