Interactions
7F1Q | CCL3_HUMAN — CCR5
SUMMARY
- Protein
- CCL3_HUMAN View protein entry
- Organism
- Homo sapiens
- UniProt ID
- P10147 View on UniProt
- PDB ID
- 7F1Q View on PDB
- Method
- Cryo-em
- Resolution
- 2.9 Å
- Date
- July 14, 2021
- Reference
- 10.1038/S41467-021-24438-5 Open DOI
- State
- Monomer
Chain information
- Chemokine chain
- R
- Partner chain
- R
3D VIEW
- Chemokine chain of interest
- GPCR
- Protein
- Antibody
- GAG
- RNA
- Peptide
- Small molecule
- Chemokine
INTERACTION TABLE
Download CSV| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Ser 1 | NTc.Cm9 | N-term | ILE 294 | R | VdWContact |
| Ser 1 | NTc.Cm9 | N-term | TYR 347 | R | HBAcceptor |
| Ser 1 | NTc.Cm9 | N-term | TYR 347 | R | VdWContact |
| Ser 1 | NTc.Cm9 | N-term | GLN 290 | R | HBDonor |
| Ser 1 | NTc.Cm9 | N-term | GLN 290 | R | VdWContact |
| Leu 2 | NTc.Cm8 | N-term | PHE 205 | R | Hydrophobic |
| Leu 2 | NTc.Cm8 | N-term | PHE 205 | R | VdWContact |
| Leu 2 | NTc.Cm8 | N-term | TRP 182 | R | VdWContact |
| Leu 2 | NTc.Cm8 | N-term | TYR 204 | R | Hydrophobic |
| Leu 2 | NTc.Cm8 | N-term | THR 201 | R | VdWContact |
| Ala 3 | NTc.Cm7 | N-term | TRP 182 | R | VdWContact |
| Ala 3 | NTc.Cm7 | N-term | GLU 379 | R | VdWContact |
| Ala 4 | NTc.Cm6 | N-term | GLU 379 | R | HBDonor |
| Ala 4 | NTc.Cm6 | N-term | GLU 379 | R | VdWContact |
| Asp 5 | NTc.Cm5 | N-term | SER 275 | R | VdWContact |
| Thr 6 | NTc.Cm4 | N-term | LYS 122 | R | HBAcceptor |
| Thr 6 | NTc.Cm4 | N-term | LYS 122 | R | VdWContact |
| Thr 6 | NTc.Cm4 | N-term | GLN 376 | R | VdWContact |
| Pro 7 | NTc.Cm3 | N-term | LYS 122 | R | HBAcceptor |
| Pro 7 | NTc.Cm3 | N-term | LYS 122 | R | VdWContact |
| Pro 7 | NTc.Cm3 | N-term | LYS 118 | R | VdWContact |
| Thr 8 | NTc.Cm2 | N-term | LYS 122 | R | VdWContact |
| Thr 8 | NTc.Cm2 | N-term | LYS 118 | R | HBAcceptor |
| Thr 8 | NTc.Cm2 | N-term | LYS 118 | R | VdWContact |
| Thr 8 | NTc.Cm2 | N-term | GLN 117 | R | VdWContact |
| Ala 9 | NTc.Cm1 | N-term | GLN 117 | R | VdWContact |
| Ala 9 | NTc.Cm1 | N-term | PRO 115 | R | VdWContact |
| Cys 10 | CX.1 | CX | LYS 118 | R | VdWContact |
| Cys 11 | CX.5 | CX | PRO 115 | R | VdWContact |
| Phe 12 | cxb1.1 | N-loop | CYS 365 | R | Hydrophobic |
| Phe 12 | cxb1.1 | N-loop | ASN 363 | R | VdWContact |
| Ser 13 | cxb1.2 | N-loop | SER 113 | R | HBDonor |
| Ser 13 | cxb1.2 | N-loop | SER 113 | R | VdWContact |
| Thr 15 | cxb1.6 | N-loop | CYS 112 | R | Hydrophobic |
| Thr 15 | cxb1.6 | N-loop | CYS 112 | R | VdWContact |
| Phe 28 | B1.6 | B1 | GLU 268 | R | VdWContact |
| Phe 28 | B1.6 | B1 | GLN 266 | R | Hydrophobic |
| Phe 28 | B1.6 | B1 | GLN 266 | R | VdWContact |
| Glu 29 | B1.7 | B1 | HIS 277 | R | Hydrophobic |
| Glu 29 | B1.7 | B1 | HIS 277 | R | VdWContact |
| Glu 29 | B1.7 | B1 | ARG 264 | R | Anionic |
| Glu 29 | B1.7 | B1 | ARG 264 | R | VdWContact |
| Glu 29 | B1.7 | B1 | GLN 266 | R | HBAcceptor |
| Glu 29 | B1.7 | B1 | GLN 266 | R | VdWContact |
| Thr 30 | b1b2.4 | 30s-loop | HIS 277 | R | VdWContact |
| Ser 31 | b1b2.6 | 30s-loop | SER 275 | R | VdWContact |
| Ser 32 | b1b2.9 | 30s-loop | SER 276 | R | VdWContact |
| Ser 32 | b1b2.9 | 30s-loop | LYS 287 | R | HBAcceptor |
| Ser 32 | b1b2.9 | 30s-loop | LYS 287 | R | VdWContact |
| Ser 32 | b1b2.9 | 30s-loop | TYR 283 | R | VdWContact |
| Gln 33 | b1b2.10 | 30s-loop | MET 375 | R | VdWContact |
| Cys 34 | b1b2.12 | 30s-loop | TYR 283 | R | HBAcceptor |
| Cys 34 | b1b2.12 | 30s-loop | TYR 283 | R | VdWContact |
| Ser 35 | b1b2.13 | 30s-loop | GLN 357 | R | VdWContact |
| Pro 37 | b1b2.16 | 30s-loop | TYR 283 | R | VdWContact |
| Gln 48 | B3.1 | B3 | SER 113 | R | VdWContact |
| Val 49 | B3.2 | B3 | CYS 112 | R | Hydrophobic |
| Val 49 | B3.2 | B3 | CYS 112 | R | VdWContact |
| Pro 53 | b3h.2 | 50s-loop | TYR 280 | R | VdWContact |
| Gln 59 | H.4 | Helix | TYR 280 | R | VdWContact |
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