Interactions
7XA3 | CCL2_HUMAN — CCR2
SUMMARY
- Protein
- CCL2_HUMAN View protein entry
- Organism
- Homo sapiens
- UniProt ID
- P13500 View on UniProt
- PDB ID
- 7XA3 View on PDB
- Method
- Cryo-em
- Resolution
- 2.9 Å
- Date
- Aug. 24, 2022
- Reference
- 10.1038/S41421-022-00403-4 Open DOI
- State
- Monomer
Chain information
- Chemokine chain
- L
- Partner chain
- R
3D VIEW
- Chemokine chain of interest
- GPCR
- Protein
- Antibody
- GAG
- RNA
- Peptide
- Small molecule
- Chemokine
INTERACTION TABLE
Download CSV| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Gln 1 | NTc.Cm10 | N-term | THR 117 | R | HBDonor |
| Gln 1 | NTc.Cm10 | N-term | THR 117 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | CYS 190 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | TYR 120 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | GLY 191 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | TRP 98 | R | Hydrophobic |
| Gln 1 | NTc.Cm10 | N-term | TRP 98 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | HIS 121 | R | VdWContact |
| Gln 1 | NTc.Cm10 | N-term | PRO 192 | R | VdWContact |
| Asp 3 | NTc.Cm8 | N-term | THR 287 | R | VdWContact |
| Asn 6 | NTc.Cm5 | N-term | CYS 190 | R | HBDonor |
| Asn 6 | NTc.Cm5 | N-term | CYS 190 | R | VdWContact |
| Asn 6 | NTc.Cm5 | N-term | GLY 191 | R | VdWContact |
| Pro 8 | NTc.Cm3 | N-term | HIS 33 | R | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | GLN 269 | R | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | CYS 32 | R | Hydrophobic |
| Tyr 13 | cxb1.1 | N-loop | CYS 32 | R | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | SER 275 | R | VdWContact |
| Tyr 13 | cxb1.1 | N-loop | THR 280 | R | VdWContact |
| Arg 29 | B1.6 | B1 | ASP 185 | R | Cationic |
| Arg 29 | B1.6 | B1 | ASP 185 | R | VdWContact |
| Ser 34 | b1b2.9 | 30s-loop | PHE 194 | R | HBDonor |
| Ser 34 | b1b2.9 | 30s-loop | PHE 194 | R | VdWContact |
| Ser 34 | b1b2.9 | 30s-loop | ASN 199 | R | VdWContact |
| Cys 36 | b1b2.12 | 30s-loop | ARG 196 | R | HBAcceptor |
| Cys 36 | b1b2.12 | 30s-loop | ARG 196 | R | VdWContact |
| Pro 37 | b1b2.13 | 30s-loop | ARG 196 | R | VdWContact |
| Glu 50 | B3.1 | B3 | PRO 31 | R | VdWContact |
| Glu 50 | B3.1 | B3 | ALA 30 | R | HBAcceptor |
| Glu 50 | B3.1 | B3 | ALA 30 | R | VdWContact |
| Cys 52 | B3.3 | B3 | ALA 30 | R | VdWContact |
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