PDB structure 7SK5
Structure details
- PDB ID: 7SK5 open_in_new
- Protein: CXCL12_HUMAN
- Organism: Homo sapiens
- UniProt ID: P48061 open_in_new
- Method: Cryo-em
- Resolution: 4.0 Å
- Date: July 27, 2022
- Reference: 10.1126/SCIADV.ABN8063 open_in_new
- State: monomer
Sequence alignment
| Segment | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 74 | 75 | 76 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 94 | 95 | 97 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 111 | 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 | 134 | 135 | 136 | 137 | 138 | 139 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProt Sequence | M | N | A | K | V | V | V | V | L | V | L | V | L | T | A | L | C | L | S | D | G | K | P | V | S | L | S | Y | R | C | P | C | R | F | F | E | S | H | V | A | R | A | N | V | K | H | L | K | I | L | N | T | P | N | C | A | L | Q | I | V | A | R | L | K | N | N | N | R | Q | V | C | I | D | P | K | L | K | W | I | Q | E | Y | L | E | K | A | L | N | K | R | F | K | M |
| Structure Sequence (Chain B) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | K | P | V | S | L | S | Y | R | C | P | C | R | F | F | E | S | H | V | A | R | A | N | V | K | H | L | K | I | L | N | T | P | N | C | A | L | Q | I | V | A | R | L | K | N | N | N | R | Q | V | C | I | D | P | K | L | K | W | I | Q | E | Y | L | E | - | - | - | - | - | - | - | - | - |
| Mutation |
Structure Entities
Anti-Fab nanobody (K)
Organism: None
UNP Accession:
PFAM Accession: None
Entity Type: Protein
Atypical chemokine receptor 3 (A)
Organism: None
UNP Accession: P25106
PFAM Accession: PF00001
Entity Type: Protein
CID24 Fab heavy chain (F)
Organism: None
UNP Accession:
PFAM Accession: None
Entity Type: Protein
CID24 Fab light chain (E)
Organism: None
UNP Accession:
PFAM Accession: None
Entity Type: Protein
Stromal cell-derived factor 1 (B)
Organism: None
UNP Accession: P48061
PFAM Accession: PF00048
Entity Type: Protein
CHOLESTEROL (A, F)
Organism: None
UNP Accession: None
PFAM Accession: None
Entity Type: Non-polymer
